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A screening test for a certain disease is prone to giving false positives or false negatives. If a patient being tested has the disease, the probability that the test indicates a (false) negative is \(.13 .\) If the patient does not have the disease, the probability that the test indicates a (false) positive is .10. Assume that \(3 \%\) of the patients being tested actually have the disease. Suppose that one patient is chosen at random and tested. Find the probability that a. this patient has the disease and tests positive b. this patient does not have the disease and tests positive c. this patient tests positive d. this patient has the disease given that he or she tests positive (Hint: A tree diagram may be helpful in part c.)

Short Answer

Expert verified
The required probabilities are: a) .0261, b) .097, c) .1231, d) .212

Step by step solution

01

Setup the Situation

Let's denote: D being the event that a patient has a disease, ¬D the event that a patient doesn't have a disease, + (Positive) being the event that a test is positive, -(Negative) being the event that a test is negative. These assertions were provided: \(P(D) = .03\), \(P(¬D) = 1 - .03 = .97\), \(P(- | D) = .13\), \(P(+ | ¬D) = .10\).
02

Calculate A Probability

a) Probability that this patient has the disease and tests positive, which is expressed as \(P(D \cap +)\). By mobility property of conditional probability we know \(P(D \cap +) = P(+ | D) * P(D)\). However, we don't know \(P(+ | D)\), but we know that the sum of probabilities of all possible events is 1. Thus, \(P(+ | D) = 1 - P(- | D) = 1 - .13 = .87\). Therefore, \(P(D \cap +) = P(+ | D) * P(D) = .87 * .03 = .0261.\)
03

Calculate B Probability

b) Probability that this patient does not have the disease and tests positive, expressed as \(P(¬D \cap +)\). We have directly from properties of conditional probability, just like step 2, that \(P(¬D \cap +) = P(+ | ¬D) * P(¬D) = .10 * .97 = .097.\)
04

Calculate C Probability

c) Probability that this patient tests positive, which is given by \(P(+) = P(D \cap +) + P(¬D \cap +) = .0261 + .097 = .1231.\)
05

Calculate D Probability

d) Probability that this patient has the disease given that he or she tests positive, expressed as \(P(D | +)\). By the definition of conditional probability, we have \(P(D | +) = \frac{P(D \cap +)}{P(+)} = \frac{.0261}{.1231} = .212\). This means, despite testing positive, there's approximately a 21.2% chance they have the disease.
06

Interpretation of Results

The high false-positive rate means that if a random person tests positive, it's still somewhat unlikely that they have the disease. Out of all the people who test positive, many of them will not have the disease, leading to a situation where a positive test result does not necessarily mean the patient has the disease.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Conditional Probability
Conditional probability helps to determine the likelihood of an event occurring given that another event has already occurred. In this exercise, we examine situations where the occurrence of a disease influences the test results. We use conditional probability to calculate the probability of various scenarios, such as testing positive only if a patient actually has the disease. The conditional probability formula is expressed as: \( P(A | B) = \frac{P(A \cap B)}{P(B)} \)where \( P(A | B) \) is the probability of event A occurring given that B is true, and \( P(A \cap B) \) is the combined probability of both events occurring together. This principle is vital because it allows us to update our beliefs about an event when more information is available. Understanding how conditional probability operates is essential for accurate analysis, especially in medical testing.
False Positives
A false positive occurs when a test incorrectly indicates the presence of a disease. In medical diagnostics, recognizing false positives is critical as they can lead to unnecessary stress and further tests for patients. Here, the probability that a person without the disease tests positive is given as \( P(+ | eg D) = 0.10 \).
Understanding false positives is crucial for interpreting test outcomes correctly. In this example, out of those who test positive, a significant number do not actually have the disease. Recognizing the potential for false positives helps in formulating realistic expectations about the test’s reliability. Moreover, it underscores the importance of considering these factors in medical decision-making to avoid unwarranted treatments and ensure effective resource allocation.
False Negatives
Conversely, a false negative occurs when a test fails to detect a disease in someone who actually has it. In our given problem, the false negative rate is \( P(- | D) = 0.13 \). False negatives can pose serious risks as they may falsely reassure patients, potentially leading to a delay in receiving necessary treatment.
Knowing the false negative ratio helps healthcare professionals assess the completeness of a test result. While our focus often leans towards false positives, understanding false negatives is equally important, as failing to acknowledge them can result in critical oversight of an existing condition. Therefore, the goal is to keep both false positive and false negative rates as low as possible, to maximize the test's accuracy and reliability.
Probability Calculations
Probability calculations involve determining the likelihood of various outcomes, given specific parameters or data sets. In our problem, these calculations guide us in finding:
  • \( P(D \cap +) \): Probability of having the disease and testing positive.
  • \( P(eg D \cap +) \): Probability of not having the disease yet testing positive.
  • \( P(+) \): Probability of testing positive.
  • \( P(D | +) \): Probability of having the disease given a positive test result.
Probability calculations allow us to navigate complex scenarios with multiple outcomes. By employing Bayes' Theorem and core principles of probability, we can determine these intricate probabilities efficiently. Properly executed probability calculations help in understanding the certainty or uncertainty associated with different outcomes, ensuring better decision-making in real-world applications such as medical testing.

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