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A screening test for a certain disease is prone to giving false positives or false negatives. If a patient being tested has the disease, the probability that the test indicates a (false) negative is .13. If the patient does not have the disease, the probability that the test indicates a (false) positive is .10. Assume that \(3 \%\) of the patients being tested actually have the disease. Suppose that one patient is chosen at random and tested. Find the probability that a. this patient has the disease and tests positive b. this patient does not have the disease and tests positive c. this patient tests positive d. this patient has the disease given that he or she tests positive

Short Answer

Expert verified
a. Approximately 0.0261, b. Approximately 0.097, c. Approximately 0.1231, d. Approximately 0.212

Step by step solution

01

Define the variables

Let's denote: D - the event that the patient has the disease, ND - the event that the patient does not have the disease, T+ the event that the test is positive, T- the event that the test is negative
02

Calculate affected population

The probability that a patient has the disease, P(D) = 0.03. The complement of this event is that the patient does not have the disease, so P(ND) = 1 - P(D) = 0.97.
03

Calculate true positive and true negative

The probability that the test is positive given the patient has the disease is P(T+|D) = 1 - 0.13 = 0.87. The probability that the test is positive given the patient does not have the disease is P(T+|ND) = 0.10.
04

Calculate the probabilities for a, b, and c

a. P(D and T+) = P(D) * P(T+|D) = 0.03 * 0.87 = 0.0261. b. P(ND and T+) = P(ND) * P(T+|ND) = 0.97 * 0.10 = 0.097. c. P(T+) = P(D and T+) + P(ND and T+) = 0.0261 + 0.097 = 0.1231.
05

Calculate the probability for d

d. P(D|T+) = P(D and T+)/P(T+) = 0.0261/0.1231 ≈ 0.212.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

False Positives
In the context of probability, especially with medical tests, understanding false positives is crucial. A false positive occurs when a test indicates the presence of a disease when, in fact, the disease is not present. This type of error can lead to unnecessary stress and additional medical tests.
In our exercise, the probability of a false positive was given to be 0.10. This means that when patients do not have the disease, there is a 10% chance that the test will wrongly indicate they do.
False positives can have wide-reaching implications, including financial costs or emotional consequences for the falsely diagnosed individual. Therefore, statistical methods like sensitivity and specificity analyses are employed to improve the accuracy of these tests.
False Negatives
False negatives are another kind of error occurring in medical testing. A false negative occurs when a test fails to detect a disease that is indeed present in the patient. For this exercise, the probability of a false negative is 0.13. Hence, a patient who actually has the disease has a 13% chance of getting a negative result.
False negatives are especially dangerous as they might lead individuals to ignore their condition and miss critical early treatment opportunities. Unlike false positives, false negatives could potentially lead to the progression of an untreated disease.
Medical tests aim to minimize false negatives through rigorous testing and validation, ensuring they are both sensitive and effective at correctly identifying the disease.
Conditional Probability
Conditional probability is a key concept in probability theory, helping us determine the likelihood of an event based on the occurrence of another related event. It's defined as \( P(A|B) \), the probability of event A occurring given that B is true.
In this exercise, one key calculation involves finding the probability that a patient has the disease given a positive test result. This is denoted as \( P(D|T+) \). Using Bayes' theorem, this conditional probability is calculated to be approximately 0.212. Bayes' theorem allows us to update the probability estimate for a hypothesis based on new evidence.
Probability Theory
Probability theory serves as the underpinning framework for these types of problems. It allows us to express uncertainty mathematically. By doing so, we can make informed predictions about random events.
Fundamental principles in probability theory include the calculation of joint probabilities and the use of complements. In our exercise, we see the practical application of these concepts.
For example, calculating the probability of false positives and negatives involves understanding complements and intersections of events. Mastery of such theories allows statisticians and scientists to predict outcomes with greater precision, fostering better decision-making in scenarios like medical testing.

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Most popular questions from this chapter

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What is meant by the joint probability of two or more events? Give one example.

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