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"Doctors Praise Device That. Aids Ailing Hearts" (Arsociated Press, November 9,2004\()\) is the headline of an article that describes the results of a study of the effectiveness of a fabric device that acts like a support stocking for a weak or damaged heart. In the study, 107 people who consented to treatment were assigned at random to either a standard treatment consisting of drugs or the experimental treatment that consisted of drugs plus surgery to install the stocking. After two years, \(38 \%\) of the 57 patients receiving the stocking had improved and \(27 \%\) of the patients receiving the standard treatment had improved. Do these data provide convincing evidence that the proportion of patients who improve is higher for the experimental treatment than for the standard treatment? 'Test the relevant hypotheses using a significance level of .05.

Short Answer

Expert verified
Based on the solution and calculations above, if the p-value obtained is less than the significance level of 0.05, it can be concluded that there is enough evidence to suggest that the experimental treatment is more effective in improving patient's condition than the standard treatment.

Step by step solution

01

Formulate the Hypotheses

Null hypothesis (H0): The proportion of patients who improve is the same for both treatments. H0: P1 = P2 \nAlternative hypothesis (H1): The proportion of patients who improve is higher for the experimental treatment than for the standard treatment. H1: P1 > P2
02

Find the Sample Proportions

Number of patients in experimental group (n1) = 57 (improved) out of 107 (total) \nProportion of patients who improved in experimental group (p1) = 38/57 = 0.67 \nNumber of patients in standard group (n2) = 50 (107-57) \nProportion of patients who improved in standard group (p2) = 27/50 = 0.54
03

Standard Error Calculation

Calculate the pooled proportion: \(p_p = (p1*n1 + p2*n2) / (n1 + n2)\) \nCalculate the standard error (SE) using the formula SE = sqrt(p_p * (1 - p_p) * [(1/n1) + (1/n2)])
04

Compute the Test Statistic

The Z score is given by: \(Z = (p1 - p2) / SE\)
05

Perform Hypothesis Test

Find the p-value corresponding to the calculated Z score. If the p-value is less than the level of significance (0.05), reject the null hypothesis.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Null Hypothesis
In hypothesis testing, the null hypothesis serves as the starting point. It is a statement that assumes no effect or no difference. That means, any observed effect in the data is due to random chance. In this particular exercise, the null hypothesis (H0) claims that there is no difference in the improvement rates between the standard treatment and the experimental one. Hence, the improvement proportions are equal: \(P_1 = P_2\). This hypothesis is what we initially assume to be true. In statistical tests, rejecting the null hypothesis implies that there is enough evidence to support the alternative hypothesis. It's like giving the existing condition the benefit of the doubt until there's sufficient evidence against it.
Alternative Hypothesis
The alternative hypothesis contradicts the null hypothesis. It suggests there is indeed an effect or difference. For this case, the alternative hypothesis (H1) asserts that the proportion of patients benefiting from the experimental treatment is greater than that of the standard treatment, or mathematically \(P_1 > P_2\). This one-sided alternative hypothesis is key when we believe there's a directional effect.
  • It conveys what the researcher expects or wishes to prove.
  • If the alternative hypothesis is true, it guides potential changes or interventions.
When conducting hypothesis testing, our goal is to see if we can gather enough data to reject the null hypothesis in favor of the alternative.
Significance Level
The significance level in a hypothesis test is a pivotal component. It helps us determine how much evidence we need to reject the null hypothesis confidently. It's usually denoted by \( \alpha \), such as 0.05, indicating a 5% risk of rejecting the null hypothesis when it's actually true (Type I error).
In this exercise, the significance level is set at 0.05. This means that if our p-value (probability of observing our sample data, given the null hypothesis) is less than 0.05, we will reject the null hypothesis.
  • The choice of \( \alpha \) influences decision-making. Lower values increase caution against false rejections, while higher values aim for detecting true effects easier.
  • Common significance levels are \(0.01\), \(0.05\), and \(0.10\).
Setting the significance level helps to balance between not missing a true effect and not raising false alarms.
Proportion Testing
Proportion testing is a statistical method used when we want to compare two different proportions. In this problem, it helps determine if the experimental treatment has a higher patient improvement rate than the standard treatment. Using proportion testing, we calculate sample proportions, pooled proportions, and standard error.
  • Sample proportions identify the ratio of successes within each group, such as the 38% and 27% improvement rates here.
  • A pooled proportion consolidates data from both groups together to figure out a collective improvement rate, assisting in error calculations.
  • The standard error gives us an understanding of sampling variability, reflecting how much the sample proportion varies from the true population proportion.
These elements are part of computing a test statistic, like the Z score, to help make conclusions about the hypothesis. If the difference in proportions is statistically significant, it suggests an effect beyond random chance.

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Most popular questions from this chapter

The paper "If It's Hard to Read, It's Hard to Do" (Psychological Science [20081: 986-988) described an interesting study of how people perceive the effort required to do certain tasks. Each of 20 students was randomly assigned to one of two groups. One group was given instructions for an exercise routine that were printed in an easy-to-read font (Arial). The other group received the same set of instructions, but printed in a font that is considered difficult to read (Brush). After reading the instructions, subjects estimated the time (in minutes) they thought it would take to complete the exercise routine. Summary statistics are given below. The authors of the paper used these data to carry out a two-sample \(t\) test, and concluded that at the 10 significance level, there was convincing evidence that the mean estimated time to complete the exercise routine was less when the instructions were printed in an easy-to-read font than when printed in a difficult-to-read font. Discuss the appropriateness of using a two-sample \(t\) test in this situation.

Consider two populations for which \(\mu_{1}=30\), \(\sigma_{1}=2, \mu_{2}=25\), and \(\sigma_{2}=3\). Suppose that two independent random samples of sizes \(n_{1}=40\) and \(n_{2}=50\) are selected. Describe the approximate sampling distribution of \(\bar{x}_{1}-\bar{x}_{2}\) (center, spread, and shape).

Women diagnosed with breast cancer whose tumors have not spread may be faced with a decision between two surgical treatments - mastectomy (removal of the breast) or lumpectomy (only the tumor is removed). In a long-term study of the effectiveness of these two treatments, 701 women with breast cancer were randomly assigned to one of two treatment groups. One group received mastectomies and the other group received lumpectomies and radiation. Both groups were followed for 20 years after surgery. It was reported that there was no statistically significant difference in the proportion surviving for 20 years for the two treatments (Associated Press, October 17,2002\()\). What hypotheses do you think the researchers tested in order to reach the given conclusion? Did the researchers reject or fail to reject the null hypothesis?

Two proposed computer mouse designs were compared by recording wrist extension in degrees for 24 people who each used both mouse types ("Comparative Study of Two Computer Mouse Designs." Cornell Human Factors Laboratory Technical Report RP7992). The difference in wrist extension was computed by subtracting extension for mouse type \(\mathrm{B}\) from the wrist extension for mouse type A for each student. The mean difference was reported to be \(8.82\) degrees. Assume that it is reasonable to regard this sample of 24 people as representative of the population of computer users. a. Suppose that the standard deviation of the differences was 10 degrees. Is there convincing evidence that the mean wrist extension for mouse type \(\mathrm{A}\) is greater than for mouse type B? Use a .05 significance level. b. Suppose that the standard deviation of the differences was 26 degrees. Is there convincing evidence that the mean wrist extension for mouse type \(\mathrm{A}\) is greater than for mouse type B? Use a .05 significance level. c. Briefly explain why a different conclusion was reached in the hypothesis rests of Parts (a) and (b).

Common Sense Media surveyed 1000 teens and 1000 parents of teens to learn about how teens are using social networking sites such as Facebook and MySpace ("Teens Show. Tell Too Much Online." San Francisco Chronicle, August 10,2009 ). The two samples were independently selected and were chosen in a way that makes it reasonable to regard them as representative of American teens and parents of American teens. a. When asked if they check their online social networking sites more than 10 times a day, 220 of the teens surveyed said yes. When parents of teens were asked if their teen checked his or her site more than 10 times a day, 40 said yes. Use a significance level of \(.01\) to carry out a hypothesis test to determine if there is convincing evidence that the proportion of all parents who think their teen checks a social networking site more than 10 times a day is less than the proportion of all teens who report that they check more than 10 times a day. b. The article also reported that 390 of the teens surveyed said they had posted something on their networking site that they later regretted. Would you use the two-sample \(z\) test of this section to test the hypothesis that more than one-third of all teens have posted something on a social networking site that they later regretted? Explain why or why not. c. Using an appropriate test procedure, carry out a test of the hypothesis given in Part (b). Use \(\alpha=.05\) for this test.

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