/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Problem 153 A biotechnology company produces... [FREE SOLUTION] | 91Ó°ÊÓ

91Ó°ÊÓ

A biotechnology company produces a therapeutic drug whose concentration has a standard deviation of 4 grams per liter. A new method of producing this drug has been proposed, although some additional cost is involved. Management will authorize a change in production technique only if the standard deviation of the concentration in the new process is less than 4 grams per liter. The researchers chose \(n=10\) and obtained the following data in grams per liter. Perform the necessary analysis to determine whether a change in production technique should be implemented. $$\begin{array}{ll}16.628 & 16.630 \\\16.622 & 16.631 \\\16.627 & 16.624 \\\16.623 & 16.622 \\\16.618 & 16.626\end{array}$$

Short Answer

Expert verified
Calculate the sample variance, perform a chi-square test, and compare against critical value to decide on the production change.

Step by step solution

01

State the Hypotheses

To determine if the production process should be changed, set up hypotheses for the standard deviation, \(\sigma\). - Null Hypothesis \(H_0\): \(\sigma = 4\) (The new method's standard deviation is not less than 4 grams per liter).- Alternative Hypothesis \(H_a\): \(\sigma < 4\) (The new method's standard deviation is less than 4 grams per liter).
02

Collect and Organize Data

List the data provided: \[16.628, 16.630, 16.622, 16.631, 16.627, 16.624, 16.623, 16.622, 16.618, 16.626\]These are the concentrations of the drug in grams per liter obtained from the new method.
03

Calculate Sample Variance

First, compute the sample mean \(\bar{x}\):\[\bar{x} = \frac{16.628 + 16.630 + 16.622 + 16.631 + 16.627 + 16.624 + 16.623 + 16.622 + 16.618 + 16.626}{10} = 16.6251\]Next, compute the sample variance \(s^2\) using the formula:\[s^2 = \frac{1}{n-1} \sum_{i=1}^{n} (x_i - \bar{x})^2\]Calculate each squared deviation and sum them.
04

Compute Test Statistic

Using the sample variance computed in Step 3, calculate the chi-square test statistic, since we're testing for variance:\[\chi^2 = \frac{(n-1)s^2}{\sigma_0^2}\]where \(\sigma_0 = 4\) is the standard deviation under the null hypothesis.
05

Determine Critical Value

Determine the critical value from the chi-square distribution table for \(\alpha = 0.05\) (typically used level of significance for a one-tailed test).Since \(n = 10\), degrees of freedom \(df = n - 1 = 9\). Find the critical value \(\chi^2_{0.05, 9}\).
06

Make the Decision

Compare the calculated chi-square statistic from Step 4 to the critical value from Step 5.- If \(\chi^2 \) is less than the critical value, reject \(H_0\). - If \(\chi^2 \) is greater than the critical value, do not reject \(H_0\).
07

Conclusion

Based on the comparison in Step 6, decide whether to adopt the new production technique:- Rejecting \(H_0\) suggests the new method's standard deviation is less than 4 grams/liter; thus, adoption is recommended.- Not rejecting \(H_0\) suggests insufficient evidence to change the process.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91Ó°ÊÓ!

Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Chi-Square Test
The Chi-Square Test is often used in statistics to test hypotheses about the variance in a given dataset. The goal is to determine if the observed variance differs significantly from the expected variance under the null hypothesis.
In the context of this exercise, we're looking at whether to switch to a new production method based on the standard deviation of drug concentration being less than 4 grams per liter.

By setting up the hypotheses, we test:
  • The Null Hypothesis \(H_0\) assumes the variance doesn't reduce (i.e., \( \sigma = 4 \)).
  • The Alternative Hypothesis \(H_a\) asserts the variance is less (i.e., \( \sigma < 4 \)).
To perform the Chi-Square Test, we need to calculate the test statistic using the formula:\[\chi^2 = \frac{(n-1)s^2}{\sigma_0^2}\]where \( n \) is the number of samples, \( s^2 \) is the sample variance, and \( \sigma_0 = 4 \) is the standard deviation given in the null hypothesis.

This test helps us evaluate if the new production method should be adopted based on whether the calculated statistic falls within a critical range indicating a significant difference.
Variance Analysis
Variance Analysis is a crucial step in understanding how the data points in a dataset deviate from the mean value. It helps us assess the variability within a set of measurements.
The formula to compute variance is:\[s^2 = \frac{1}{n-1} \sum_{i=1}^{n} (x_i - \bar{x})^2\]Here, \( s^2 \) represents the sample variance, \( n \) is the number of observations, and \( \bar{x} \) is the sample mean.

This measure gives insight into the spread of the data points. A smaller variance signifies that the data points are closer to the mean, which in this problem, would show that the new method controls the concentration of the drug effectively.
  • Calculate the average or mean value of the dataset.
  • Compute each deviation squared (difference from the mean squared).
  • Sum these squared deviations.
Variance analysis, in this context, informs if the new method results in a significant decrease in variability compared to the current method, thus being crucial to deciding the method’s implementation.
Standard Deviation
Standard Deviation is a statistical measure that provides an estimate of how much individual data points in a dataset differ from the mean. It is the square root of the variance and provides a clearer picture of the spread of a data set.

For this exercise, the important comparison revolves around whether the standard deviation of concentrations produced by the new method is less than 4 grams per liter.
The relationship can be expressed as:\[\sigma = \sqrt{s^2}\]where \( \sigma \) is the standard deviation and \( s^2 \) is the variance.

Standard deviation is particularly useful when interpreting the consistency of a production method. A smaller standard deviation indicates that results are consistently close to the mean, implying repeatability and precision. This is crucial for processes like drug production where consistent quality is necessary.
  • It provides insights into data reliability.
  • Helps in comparing different methodologies for their effectiveness.
  • Assists in quality control by monitoring process deviations.
Understanding and managing the standard deviation helps in ensuring the new production method keeps the variability in check, aligning with the quality standards expected.

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Consider the computer output below Test of \(p=0.25\) vs \(p<0.25\) $$\begin{array}{cccccc}\mathrm{X} & \mathrm{N} & \text { Sample } p & \text { Bound } & Z \text { -Value } & P \text { -Value } \\\53 & 225 & 0.235556 & 0.282088 & ? & ?\end{array}$$ Using the normal approximation: (a) Fill in the missing information. (b) What are your conclusions if \(\alpha=0.05 ?\) (c) The normal approximation to the binomial was used here. Was that appropriate? (d) Find a \(95 \%\) upper-confidence bound on the true proportion. (e) What are the \(P\) -value and your conclusions if the alternative hypothesis is \(H_{1}: p \neq 0.25 ?\)

A 1992 article in the Journal of the American Medical Association ("A Critical Appraisal of 98.6 Degrees \(\mathrm{F}\), the Upper Limit of the Normal Body Temperature, and Other Legacies of Carl Reinhold August Wunderlich") reported body temperature, gender, and heart rate for a number of subjects. The body temperatures for 25 female subjects follow: 97.8,97.2,97.4,97.6 97.8,97.9,98.0,98.0,98.0,98.1,98.2,98.3,98.3,98.4,98.4 \(98.4,98.5,98.6,98.6,98.7,98.8,98.8,98.9,98.9,\) and \(99.0 .\) (a) Test the hypothesis \(H_{0}: \mu=98.6\) versus \(H_{1}: \mu \neq 98.6,\) using \(\alpha=0.05 .\) Find the \(P\) -value. (b) Check the assumption that female body temperature is normally distributed. (c) Compute the power of the test if the true mean female body temperature is as low as \(98.0 .\) (d) What sample size would be required to detect a true mean female body temperature as low as 98.2 if you wanted the power of the test to be at least \(0.9 ?\) (e) Explain how the question in part (a) could be answered by constructing a two-sided confidence interval on the mean female body temperature.

A Grades in a statistics course and an operations research course taken simultaneously were as follows for a group of students. $$\begin{array}{ccccc} & {\text { Operation Research Grade }} \\\\\hline \text { Statistics Grade } & \mathbf{A} & \mathbf{B} & \mathbf{C} &\text { Other } \\\\\text { A } & 25 & 6 & 17 & 13 \\\\\text { B } & 17 & 16 & 15 & 6 \\\\\text { C } & 18 & 4 & 18 & 10 \\\\\text { Other } & 10 & 8 & 11 & 20 \\\\\hline\end{array}$$ Are the grades in statistics and operations research related? Use \(\alpha=0.01\) in reaching your conclusion. What is the \(P\) -value for this test?

Consider the test of \(H_{0}: \sigma^{2}=5\) against \(H_{1}: \sigma^{2}<5 .\) Approximate the \(P\) -value for each of the following test statistics. (a) \(x_{0}^{2}=25.2\) and \(n=20\) (b) \(x_{0}^{2}=15.2\) and \(n=12\) (c) \(x_{0}^{2}=4.2\) and \(n=15\)

The mean pull-off force of an adhesive used in manufacturing a connector for an automotive engine application should be at least 75 pounds. This adhesive will be used unless there is strong evidence that the pull-off force does not meet this requirement. A test of an appropriate hypothesis is to be conducted with sample size \(n=10\) and \(\alpha=0.05 .\) Assume that the pull-off force is normally distributed, and \(\sigma\) is not known. (a) If the true standard deviation is \(\sigma=1\), what is the risk that the adhesive will be judged acceptable when the true mean pull-off force is only 73 pounds? Only 72 pounds? (b) What sample size is required to give a \(90 \%\) chance of detecting that the true mean is only 72 pounds when \(\sigma=1 ?\) (c) Rework parts (a) and (b) assuming that \(\sigma=2\). How much impact does increasing the value of \(\sigma\) have on the answers you obtain?

See all solutions

Recommended explanations on Math Textbooks

View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.