Q18P a. Show how to synthesize the follo... [FREE SOLUTION]

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Chapter 20: Q18P a. (page 1065)

Show how to synthesize the following compounds, using appropriate carboxylic acids and amines.
(a)
(b)
(c)

Short Answer

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(a)

(b)

(c)

Step by step solution

Amines and carboxylic acids

Amines are compounds containing the -NH₂group and carboxylic compounds with the 鈥揅OOH group.Different reagents are used to prepare acid derivatives, such as amide $HN {({CH}_{2} {CH}_{3})}_{2}$ is used. The formation of amide by using industrial methods needs high temperature.

Synthesis of N, N-diethyl-meta-toluamide

(a) When 3-methyl benzoic acid is treated with $HN {({CH}_{2} {CH}_{3})}_{2}$ , a carboxylate anion is formed and, on heating, ${COO}^{-}$ is converted to ${CONEt}_{2}$ . The product created is N, N-diethyl-meta-toluamide.

Synthesis of N, N-diethyl-meta-toluamide

Synthesis of acetanilide

(b) When aniline is treated with acetic acid , an acetate ion is formed along with a phenyl ammonium ion. Further, on heating, acetanilide is formed.

Reaction of acetanilide

Synthesis of acetanilide

Synthesis of N, N-dimethylformamide(DMF)

(c) When aniline is treated with acetic acid (CH₃COOH) , an acetate ion is formed along with a phenyl ammonium ion. Further, on heating, acetanilide is formed.