/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Q36P-a Show how you would accomplish th... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 21: Q36P-a (page 1129)

Show how you would accomplish the following synthetic transformations. You may use any necessary reagents.(a)N-ethylbenzamide鈫�benzylethylamine

Short Answer

Expert verified

Synthetic transformation for N-ethylbenzamide to benzylethylamine is show as,

Step by step solution

01

Step-by-Step SolutionStep 1: Use of  LiAIH4reagent

LiAIH4is a strong reducing agent for polar double bonds, as it easily thought of as a source of H鈭� . It will reduce aldehydes, ketones,esters, carboxylic acid chloride, carboxylic acids and even carboxylate salts to alcohols.


LiAIH4is also reduce the amide and nitriles to amine, In above reaction amide is reduce to amine.

02

Synthesis of benzylethylamine from N-ethylbenzamide

When N-ethylbenzamide react withLiAIH4andH2Othen there is a formation of benzylethylamine, in this reaction carbonyl group are direct reduce to alkane.

Formation of benzylethylamine

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

When ethyl 4-hydroxybutyrate is heated in the presence of a trace of a basic catalyst (sodium acetate), one of the products is a lactone. Propose a mechanism for the formation of this lactone.

Name the following carboxylic acid derivatives, giving both a common name and an IUPAC name where possible.

a.

b.

c.

d.

e.

f.

g.

h.

i.

j.

k.

l.

m.

n.

o.

p.

q.

r.

Show how you would accomplish the following syntheses using amides as intermediates.

You may use any necessary reagents.

(a)benzoicacid鈫�benzyldimethylamine

Macrolide antibiotics, including erythromycin and azithromycin (), contain a large ring lactone. One of the largest ever reported is Gargantulide A, the structure of which was determined by the research group of Prof. William Gerwick of the Scripps Institution of Oceanography (Organic Letters, 2015, 17, 1377鈥�1380). Isolated from a Streptomyces bacterium, it kills pathogenic bacteria like MRSA and Clostridium difficile, but it proved too toxic to the test animals to continue further testing.

(a) Identify the lactone that makes this a macrolide structure.

(b) How many rings does this structure contain? How many atoms are in the largest ring?

(c) Many complex NMR experiments were used to determine the stereochemistry of most, but not all, of the chiral centers. How many chiral centers does the structure contain?

Show how you would synthesize the following esters from appropriate acyl chlorides and alcohols.

(a) ethyl propionate

(b)phenyl 3-methylhexanoate

(c)benzyl benzoate

(d)cyclopropyl cyclohexanecarboxylate

(e)tert-butyl acetate

(f) diallyl succinate
See all solutions

Recommended explanations on Chemistry Textbooks

Chemical Reactions

Read Explanation

Chemistry Branches

Read Explanation

Physical Chemistry

Read Explanation

Chemical Analysis

Read Explanation

Making Measurements

Read Explanation

The Earths Atmosphere

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.