Chapter 24: Problem 26
Give the general formula for any cyclic alkene, that is, a cyclic hydrocarbon with one double bond.
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Chapter 24: Problem 26
Give the general formula for any cyclic alkene, that is, a cyclic hydrocarbon with one double bond.
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Describe the intermediate that is thought to form in the addition of a hydrogen halide to an alkene, using cyclohexene as the alkene in your description.
(a) What is the empirical formula of cellulose? (b) What is the monomer that forms the basis of the cellulose polymer? (c) What bond connects the monomer units in cellulose: amide, acid, ether, ester, or alcohol?
Indicate whether each statement is true or false. (a) The sequence of amino acids in a protein, from the amine end to the acid end, is called the primary structure of the protein. (b) Alpha helix and beta sheet structures are examples of quaternary protein structure. (c) It is impossible for more than one protein to bind to another and make a higher order structure.
Write a chemical equation for the formation of methionyl-glycine from the constituent amino acids.
The protein ribonuclease \(A\) in its native, or most stable, form is folded into a compact globular shape: (a) Does the native form have a lower or higher free energy than the denatured form, in which the protein is an extended chain? (b) What is the sign of the system's entropy change in going from the denatured to the folded form? (c) In the native form, the molecule has four \(-\mathrm{S}-\mathrm{S}-\) bonds that bridge parts of the chain. What effect do you predict these four linkages to have on the free energy and entropy of the native form relative to the free energy and entropy of a hypothetical folded structure that does not have any \(-\mathrm{S}-\mathrm{S}-\) linkages? Explain. (d) A gentle reducing agent converts the four \(-\mathrm{S}-\mathrm{S}-\) linkages in ribonuclease \(\mathrm{A}\) to eight \(-\mathrm{S}-\mathrm{H}\) bonds. What effect do you predict this conversion to have on the tertiary structure and entropy of the protein? (e) Which amino acid must be present for \(-\mathrm{SH}\) bonds to exist in ribonuclease A?
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