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Human beings carrying the dominant allele \(T\) can taste the substance phenylthiocarbamide (PTC). In a population in which the frequency of this allele is \(0.4,\) what is the probability that a particular taster is homozygous?

Short Answer

Expert verified
The probability is 0.16.

Step by step solution

01

Understand Allele Frequencies

In this context, allele frequencies refer to the proportion of different versions of a gene present in a population. We are given that the frequency of the dominant allele \( T \) (which allows tasting of PTC) is \( 0.4 \). Hence, \( f(T) = 0.4 \).
02

Define Complementary Frequency

Since there are only two alleles (dominant \( T \) and recessive \( t \)), the frequency of the recessive allele \( t \) is \( 1 - f(T) \). Thus, \( f(t) = 1 - 0.4 = 0.6 \).
03

Identify Homozygous Configuration

A homozygous taster possesses two dominant alleles, represented as \( TT \). The probability of being homozygous for the tasting allele is found using the frequency of the \( T \) allele.
04

Calculate Homozygous Probability Using Hardy-Weinberg Principle

The probability of an individual being homozygous dominant \( TT \) is calculated as \( (f(T))^2 \). Substitute the given frequency to find \( (0.4)^2 = 0.16 \).
05

Conclusion

The probability that a particular taster is homozygous (i.e., has \( TT \) genotype) is \( 0.16 \).

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Hardy-Weinberg principle
The Hardy-Weinberg principle is a key concept in population genetics. It provides a model that helps us understand how allele frequencies should behave in a sexually reproducing population under ideal conditions. These conditions include: no mutation, random mating, no natural selection, infinite population size, and no migration. Using this principle, scientists can predict the genetic makeup of a population. The principle states that allele and genotype frequencies will remain constant from generation to generation in the absence of evolutionary influences. This concept is often used to estimate the frequencies of various genotypes within a population by using the relationship \[p^2 + 2pq + q^2 = 1\]where \( p \) is the frequency of one allele, and \( q \) is the frequency of the other allele. This equation enables the calculation of the expected proportions of homozygous (both dominant and recessive) and heterozygous genotypes. As seen in the original exercise, the Hardy-Weinberg principle is used to calculate the probability of specific genotypes, reinforcing its critical role in understanding genetic variation.
homozygosity
Homozygosity refers to having two identical alleles for a particular gene. In genetics, when an organism inherits two copies of the same allele, it is termed homozygous. In the given problem, a taster who is homozygous possesses two dominant alleles, or the genotype is represented as \( TT \).The degree of homozygosity within a population can profoundly impact its genetic diversity. Homozygosity can influence various traits, including vulnerability to certain diseases. In situations where the dominant allele frequency is known, the probability of an individual being homozygous dominant can be calculated by squaring the allele frequency, as shown in the Hardy-Weinberg equation: \[(f(T))^2 = (0.4)^2 = 0.16\]This solution illustrates that 16% of the population will be homozygous dominant for the taster trait.
genetic probability
Genetic probability is a fascinating area in genetics that deals with the likelihood of inheriting certain traits or genotypes. By understanding genetic probability, we can predict the distribution of alleles and genotypes in future generations.This requires knowing the frequency of alleles in a given population, which is a cornerstone for calculating probabilities of genetic outcomes. For example, in the PTC taste case, we start with the allele frequency of the tasting gene \( T \). Once the frequency of \( T \) (\( f(T) = 0.4 \)) is established, calculating the likelihood of homozygous occurrences is a straightforward application of probability theory.Importantly, genetic probabilities do not just reflect individual outcomes but provide insights into the population's structure and its genetic health. It helps understand how certain traits are perpetuated in populations and can indicate if a population might be at risk for genetic disorders due to high homozygosity.

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Most popular questions from this chapter

For each set of relative fitnesses for the genotypes \(A A\) \(A a,\) and \(a a,\) explain how selection is operating. Assume that \(0

Each of two isolated populations is in Hardy-Weinberg equilibrium with the following genotype frequencies: $$\begin{array}{llll} \text { Genotype: } & A A & A a & a a \\ \text { Frequency in Population 1: } & 0.04 & 0.32 & 0.64 \\ \text { Frequency in Population 2: } & 0.64 & 0.32 & 0.04 \end{array}$$ (a) If the populations are equal in size and they merge to form a single large population, predict the allele and genotype frequencies in the large population immediately after merger. (b) If the merged population reproduces by random mating, predict the genotype frequencies in the next generation. (c) If the merged population continues to reproduce by random mating, will these genotype frequencies remain constant?

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