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91Ó°ÊÓ

Problem 1

Which of the following vectors would be able to carry the designed transcription unit? a. HSV amplicon vector b. Recombinant AAV vector c. Lentivirus-based vector d. Adenovirus-based vector e. All of the above

Problem 3

Select the viral vector(s) that would be able to harbor a 2 kb transcription unit? a. Adenovirus vectors b. Adeno-associated virus vectors c. Murine oncoretrovirus vectors d. Lentivirus vectors e. Recombinant HSV vectors f. HSV amplicon vectors

Problem 4

Select the viral vector(s) that would be able to harbor a \(15 \mathrm{~kb}\) transcription unit? a. Adenovirus vectors b. Adeno-associated virus vectors c. Murine oncoretrovirus vectors d. Lentivirus vectors e. Recombinant HSV vectors f. HSV amplicon vectors

Problem 5

Which of the following considerations takes into account transcriptionally regulating what cell type a particular transgene is expressed within? a. Focal tissue delivery b. Promoter selection c. Transgene glycosynthesis d. Trypan blue e. Virus tropism

Problem 6

Which of the following viral vector(s) delivers a genome that is episomally maintained in the transduced host cell nucleus? a. Adenovirus vectors b. Murine oncoretrovirus vectors c. Lentivirus vectors d. Recombinant HSV vectors e. HSV amplicon vectors

Problem 7

Which of the following viral vector(s) delivers a genome that integrates in the transduced host cell genome? a. Adenovirus vectors b. HSV amplicon vectors c. Lentivirus vectors d. Replication-restricted HSV vectors e. Recombinant HSV vectors

Problem 9

Name the two non-coding sequences derived from HSV that are included in HSV amplicon vectors.

Problem 10

What is a single-chain antibody?

Problem 11

What is the difference between active and passive immunization?

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