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Problem 1

Which of the following is/are true regarding the endocrine system? a composed of specialized tissues or glands b hormones are released into the bloodstream c transmission is rapid throughout the body d all of the above e a and b.

Problem 2

In normal replacement therapy of a hypofunctioning gland, which of the following will apply? a a pharmacological dose is most advantageous b a physiological dose will not be sufficient to compensate c a pharmacological dose is the only way to cure the disease d a physiological dose is generally most appropriate e a physiological dose is the only way to cure a disease.

Problem 3

Which of the following occurs with insulin-dependent, juvenile-onset, type 1 diabetes? a overactivity of the beta cells of the pancreas b elevated blood insulin levels c increase in body weight d reduced blood glucose levels e decrease in body weight.

Problem 4

Which of the following is/are the cause of death in untreated insulin- dependent, juvenile-onset, type 1 diabetes? a excess blood glucose b excess urine formation c kidney failure d ketoacidosis e none of the above.

Problem 5

Which of the following is/are true regarding insulin? a it is a low-molecular-weight steroid b it is produced in the alpha cells of the pancreas c it is used in type 1 diabetes d it is always used in type 2 diabetes e a and c.

Problem 6

The first commercial insulin preparations were obtained from which of the following? a slaughtered pigs b human cadavers c slaughtered cows d slaughtered sheep e a and c.

Problem 7

Which of the following is/are true of today’s insulin preparations? a differ in onset and duration of action b are primarily produced by recombinant technology c are less antigenic since they are based upon human insulin d offer no advantage over bovine or porcine insulin e a, b, and c above.

Problem 8

Hypofunctioning of which gland is particularly significant in neonates? a adrenal b ovary c testes d liver e thyroid.

Problem 9

The principal mechanism of action of combination oral contraceptive agents is which of the following? a altered oviduct motility b induction of pre-ovulation c inhibition of ovulation d direct inhibitory effect on the ovaries e none of the above.

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