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Chapter 9: Problem 14

List the steps in DNA replication.

Short Answer

Expert verified
The DNA replication steps are: 1. Unzipping of DNA 2. Binding of RNA primers 3. Replication with DNA Polymerase 4. Removal of RNA primers 5. Sealing of new strands.

Step by step solution

01

Unzipping DNA

The first step in DNA replication is the separation of the two strands that make up the DNA molecule. This breaking of hydrogen bonds between bases and the subsequent 'unzipping' of DNA is facilitated by an enzyme called DNA helicase.
02

Binding of RNA Primers

Once the DNA is unzipped, an enzyme called primase synthesizes an RNA primer, or primers, which are starting points for DNA synthesis.
03

Replication with DNA Polymerase

In the third step, an enzyme called DNA polymerase adds DNA nucleotides to the RNA primer. DNA polymerase 'reads' the existing DNA strands to create two new strands that match the existing ones.
04

Removal of RNA Primers

Once the DNA replication is finished, another enzyme, RNase H, removes the RNA primer, and a different DNA polymerase fills in the resultant gaps with DNA.
05

Sealing of New Strands

In the final step of DNA replication, an enzyme called DNA ligase seals up the fragments of DNA into a continuous double strand.

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Most popular questions from this chapter

How does a purine differ from a pyrimidine?

Distinguish between the locations of the phosphodiester bonds and the hydrogen bonds in a DNA molecule.

Why must DNA be replicated continuously as well as discontinuously?

How does RNA participate in DNA replication?

Place in increasing size order: nucleosome, histone protein, and chromatin.
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