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Chapter 8: Problem 8

An inversion heterozygote has the following inverted chromosome: What would be the products if a crossover occurred between genes \(H\) and \(I\) on the inverted chromosome and a normal chromosome?

Short Answer

Expert verified
The crossover between genes \(H\) and \(I\) on the inverted chromosome and a normal chromosome would result in two chromosomes, one with genes preceding \(H\) in original order followed by an inverted segment from \(I\), and the other with genes after \(I\) in their original order followed by an inverted segment from \(H\). This can potentially lead to genetic disorders.

Step by step solution

01

Understand Chromosomal Inversion

In the context of genetics, an inversion is a mutation which causes a reversal in the order of a segment of a chromosome. In this exercise, this inverted chromosome is referred to as an inversion heterozygote. Heterozygote would mean that one of the two chromosomes is inverted and the other one is normal.
02

Understand Crossover

Crossover is a process that happens during meiosis, where two chromosomes pair up and exchange segments of their genetic material. This results in a recombination of maternal and paternal genes. Here, it is important to understand that it is specified that a crossover occurs between genes \(H\) and \(I\), which means segments containing these genes are exchanged between the inverted and the normal chromosome.
03

Predict Resulting Structures

The crossover between genes \(H\) and \(I\) will result in two recombinant structures. On one chromosome, genes preceding \(H\) will maintain their original order, followed by an inverted segment starting from gene \(I\) to the end of the chromosome. On the other chromosome, genes after \(I\) will keep their initial order, followed by an inverted segment starting from gene \(H\) to the end of the chromosome.
04

Assess Genetic Consequences

The genetic consequence of such a crossover is that the offspring's genetic makeup will be a combination of parental genes, but the gene order will be affected if the crossover occurs in the inverted region, that can lead to genetic disorders if gene sequences in these regions are critical for survival or development.

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Most popular questions from this chapter

A person is born with one \(\mathrm{X}\) chromosome, zero \(\mathrm{Y}\) chromosomes, trisomy 21 , and two copies of the other chromosomes. How many chromosomes does this person have altogether? Explain whether this person is euploid or aneuploid.

A diploid fruit fly has eight chromosomes. How many total chromosomes would be found in the following flies? A. Tetraploid B. Trisomy 2 C. Monosomy 3 D. \(3 n\) E. \(4 n+1\)

A cytogeneticist has collected tissue samples from members of a certain butterfly species. Some of the butterflies were located in Canada, and others were found in Mexico. Through karyotyping, the cytogeneticist discovered that chromosome 5 of the Canadian butterflies had a large inversion compared with chromosome 5 of the Mexican butterflies. The Canadian butterflies were inversion homozygotes, whereas the Mexican butterflies had two normal copies of chromosome \(5 .\) A. Explain whether a mating between Canadian and Mexican butterflies would produce phenotypically normal offspring. B. Explain whether the offspring of a cross between Canadian and Mexican butterflies would be fertile.

A zookeeper has collected a male and a female lizard that look like they belong to the same species. They mate with each other and produce phenotypically normal offspring. However, the offspring are sterile. Suggest one or more explanations for their sterility.

Two phenotypically normal parents produce a phenotypically abnormal child in which chromosome 5 is missing part of its long arm but has a piece of chromosome 7 attached to it. The child also has one normal copy of chromosome 5 and two normal copies of chromosome 7. With regard to chromosomes 5 and 7 , what do you think are the chromosomal compositions of the parents?
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