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Chapter 14: Problem 3

If a gene is repressible and under positive control, what kind of effector molecule and regulatory protein are involved in its regulation? Explain how the binding of the effector molecule affects the regulatory protein.

Short Answer

Expert verified
In the case of a repressible gene under positive control, the effector molecule is a co-repressor and the regulatory protein involved is an activator. When the co-repressor binds to the activator, it inhibits the activator's run in enhancing the gene transcription process, hence repressing it.

Step by step solution

01

Understanding key terms

At first, it's essential to understand what is meant by a repressible gene and positive control. A repressible gene is one that usually expresses and produces a protein unless it is repressed. Positive control, on the other hand, means that the process of transcription is activated by a regulatory protein binding to DNA.
02

Identifying the effector molecule and regulatory protein

In the case of a repressible gene under positive control, the effector molecule would be a co-repressor and the regulatory protein would be an activator. Co-repressor is the molecule that binds the activator protein, reducing its ability to promote transcription. The activator protein is the regulatory protein that binds to DNA and aids in transcribing the gene.
03

Explaining the impact of effector molecule binding

When the co-repressor (effector molecule) binds to the activator (regulatory protein), it inhibits its ability to enhance the transcription process. Since this is a repressible gene and, the gene, under normal conditions, transcribes and translates, the process prevails unless it's repressed. This repression takes place when the co-repressor binds with the activator inhibiting further gene transcription.

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Most popular questions from this chapter

What is meant by the term attenuation? Is it an example of gene regulation at the level of transcription or translation? Explain your answer.

Using three examples, describe how allosteric sites are important in the function of genetic regulatory proteins.

Some mutations have a cis-effect, whereas others have a transeffect. Explain the molecular differences between cis- and transmutations. Which type of mutation (cis or trans) can be complemented in a merozygote experiment?

What is the difference between a constitutive gene and a regulated gene?

Mutations may have an effect on the expression of the lac operon and the trp operon. Would the following mutations have a cis- or transeffect on the expression of the protein-encoding genes in the operon? A. A mutation in the operator site that prevents lac repressor from binding to it B. A mutation in the lacI gene that prevents lac repressor from binding to DNA C. A mutation in the \(\operatorname{trp} L\) gene that prevents attenuation
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