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Chapter 11: Problem 17

Draw a picture that illustrates how DNA helicase works.

Short Answer

Expert verified
The illustration will depict a segment of DNA being 'unzipped' by DNA helicase. The DNA before the helicase will be shown as a double helix, with the DNA after the helicase shown as two separate strands. This illustrates the process of DNA replication as helicase breaks the bonds between base pairs.

Step by step solution

01

Draw DNA Helix

Start by drawing a double helix which represents the DNA. Make sure to show the two strands of the helix and the rungs of the ladder that represent the base pairs bonded together.
02

Draw DNA Helicase and Broken Bonds

Indicate where the DNA helicase is attached on the DNA strand. Draw it unzipping the DNA by breaking the hydrogen bonds between the base pairs. This can be represented by a fork-like separation at the point where DNA helicase is located.
03

Show Separated DNA Strands

After the point of the DNA helicase, draw the separated strands of the DNA that are 'unzipped'. This portrays the resulting replication fork with two single-stranded DNA ready to be replicated.
04

Highlight DNA Helicase

Finally, it may be helpful to highlight or label DNA helicase in the picture, to draw attention to it and ensure that its crucial role in the process is clear.

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Most popular questions from this chapter

A DNA strand has the following sequence: 5'-GATCCCGATCCGCATACATTTACCAGATCACCACC \(-3^{\prime}\) In which direction would DNA polymerase slide along this strand (from left to right or from right to left)? If this strand was used as a template by DNA polymerase, what would be the sequence of the newly made strand? Indicate the \(5^{\prime}\) and \(3^{\prime}\) ends of the newly made strand.

Discuss the similarities and differences in the synthesis of DNA in the lagging and leading strands. What is the advantage of a primosome and a replisome as opposed to having all replication enzymes functioning independently of each other?

What enzymatic features of DNA polymerase prevent it from replicating one of the DNA strands at the ends of linear chromosomes? Compared with DNA polymerase, how is telomerase different in its ability to synthesize a DNA strand? What does telomerase use as its template for the synthesis of a DNA strand? How does the use of this template result in a telomere sequence that is tandemly repetitive?

Single-strand binding proteins keep the two parental strands of DNA separated from each other until DNA polymerase has an opportunity to replicate the strands. Suggest how single-strand binding proteins keep the strands separated and yet do not impede the ability of DNA polymerase to replicate the strands.

What is an Okazaki fragment? In which strand of replicating DNA are Okazaki fragments found? Based on the properties of DNA polymerase, why is it necessary to make these fragments?
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