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Chapter 6: Q11. (page 158)

Why do turns and loops most often occur on the protein surface?

Short Answer

Expert verified

The loops and turns often occur on the protein surface because of their hydrophilic residues.

Step by step solution

01

Loops and turns

The loops and turns are the regions of proteins that connect the 伪 helices and 尾 sheets or strands. It allows polypeptide chains to form a more compact structure. They are primarily composed of hydrophilic residues.

02

Position of loops and turns

The hydrophilic residues of the loops and turns extend toward the surface of the protein, where they are in contact with the aqueous solvent. Also, they shelter the hydrophobic residues of the protein toward the core of the protein.

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Most popular questions from this chapter

Globular proteins are typically constructed from several layers of secondary structure, with a hydrophobic core and a hydrophilic surface. Is this true for a fibrous protein such as 伪 keratin?

Describe the features of the amino acid sequences that are necessary to form a coiled coil or a left-handed triple helix.

Is it possible for a native protein to be entirely irregular鈥攖hat is, without 伪 helices, 尾 sheets, or other repetitive secondary structures?

(a) Is Trp or Gln more likely to be on a protein鈥檚 surface? (b) Is Ser or Val less likely to be in a protein鈥檚 interior? (c) Is Leu or Ile less likely to be found in a middle of an 伪 helix? (d) Is Cys or Ser more likely to be in a 尾 sheet?

Describe the forces that stabilize proteins, and rank their relative importance.
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