Chapter 7: Q11P (page 219)
Is myosin a fibrous protein or a globular protein? Explain.
Short Answer
Myosin is both a fibrous and a globular protein.
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Chapter 7: Q11P (page 219)
Is myosin a fibrous protein or a globular protein? Explain.
Myosin is both a fibrous and a globular protein.
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If myoglobin had the same p50 value as hemoglobin, how well would it facilitate O2 diffusion under the conditions described in Problem 21?
What is the likely range of the Hill constant for the hemoglobin described in Problem 23?
Explain why mutations can increase or decrease the oxygen affinity and cooperativity of hemoglobin. How can the body compensate for those changes?
In hemoglobin Rainier, Tyr 145β is replaced by Cys, which forms a disulfide bond with another Cys residue in the same subunit. This prevents the formation of ion pairs that normally stabilize the T state. How does hemoglobin Rainier differ from normal hemoglobin with respect to (a) oxygen affinity, (b) the Bohr effect, and (c) the Hill constant?
How many hypervariable loops are present in (a) IgG and (b) IgM?
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