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Chapter 24: Q31P (page 876)

Compounds known as peptide nucleic acids (PNAs) have been developed as nucleic acid-binding probes. A PNA molecule has a polypeptide-like backbone with purine and pyrimidine bases attached as side chains. Draw the PNA backbone resulting from amide bond formation between two molecules ofN-(2-aminoethyl)glycine.

Short Answer

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Following is the PNA backbone resulting from amide bond formation between two molecules of N-(2-aminoethyl)glycine:

Step by step solution

01

Definition of Amide bond

Amides are functional groups in which a carbonyl carbon atom is linked to a nitrogen atom, as well as a hydrogen or carbon atom, by a single bond.

02

Draw the PNA backbone resulting from the amide bond

Nucleic acid mimics are peptide nucleic acids (PNAs). They're created in a lab for scientific purposes. They've recently been used in diagnostic assays and antisense treatments.

The backbone of the PNA is made up of two N -(2-aminoethyl)glycine molecules joined by a peptide link.

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