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The diameter of the KcsA K+channel is ~6A°. Why can't H2O(diameter 2.75A°) pass through this channel?

Short Answer

Expert verified

The K+ion within the channel restricts the entry of water molecule by hydrogen bond creation.

Step by step solution

01

Trans membrane protein

Trans-membrane proteins known as K+channel passively transportpotassium ions from the cytoplasm to the extracellular environment.Streptomyces lividons has a K+channel called KcsA. The integral membrane protein KcsA has 158 residues.

02

Water cannot pass through the potassium channel

KcsAK+channel has a diameter of 6A°, whereasH2Ois 2.758. KcsAK+channels have a large central pore area, allowing hydrated K to pass through.

The pore’s top portion is filtered selectively, causing a transiting ion to obstruct the water hydration route into the KcsA K+channel. By causing ahydrogen-bond modification, the K+ion within the channel prevents water molecules from accessing.

Hence, the ion within the channel preventswater molecules from entering by altering the hydrogen bond.

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