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Chapter 10: Q10_17P (page 319)

What happens to K+transport by valinomycin when the membrane is cooled below its transition temperature?

Short Answer

Expert verified

The transport of K+ion stops through valinomycin when the temperature of the membrane reaches below the transition temperature.

Step by step solution

01

Introduction

Valinomycin is a well-studied ionophore that binds specifically to a K+ion. It's a cyclic ionophore withester linkage, peptide bonds, and D and L-amino acids.

02

Changes occur in  transport

Valinomycin is a channel-formingionophorethat creates transmembrane channels or pores that allow chosen ions to flow through. When the membrane is cooled below the transition temperature, the lipids become immobilization in agel-like state. It makes theionophore-K complex unable to diffuse through the membrane causing the transport to be terminated.

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Most popular questions from this chapter

How can you predict whether it will be thermodynamically favorable for an uncharged substance to move from one side of a membrane to the other?

Which transporters provide an open passageway for the transmembrane movement of a solute? Which transporters undergo a conformational change as part of their transport mechanism?

BIOINFORMATICS
Brief Exercises Brief, online bioinformatics homework exercises can be
found in WileyPLUS Learning Space.
Exercise 1 Porins: Maltoporin and Ompf
Exercise 2 lon Channels

Why would overexpression of an MDR transporter in a cancer cell make cancer more difficult to treat?

Indicate whether the following compounds are likely to cross a membrane by nonmediated or mediated transport: (a) ethanol, (b) glycine, (c)cholesterol, (d) ATP.
See all solutions

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