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Chapter 22: Q1CP (page 781)

Summarize the importance of pyruvate and acetyl-CoA for catabolism and Anabolism.

Short Answer

Expert verified

Pyruvate is used to produce acetyl-CoA, forms oxaloacetate, and gives rise to glucose or certain amino acids.

Acetyl CoA is used to synthesize ketone body and fatty acids.

Step by step solution

01

Step 1:Catabolism and Anabolism

Metabolism (chemical reaction occurring in organism bodies) is of two types which are as follows:

  • Catabolism - complex compounds are broken down into simple molecules.
  • Anabolism 鈥� simpler molecule joined to form a complex molecule.
02

Importance of pyruvate and acetyl-CoA

The importance of pyruvate and acetyl-CoA in the catabolism and anabolism process is as follows:

  • Pyruvate on oxidatively decarboxylated produced acetyl-CoA, thereby applying its atoms in oxidation or the biosynthesis of fatty acids. It also forms oxaloacetate by pyruvate carboxylase reaction, which gives rise to glucose or certain amino acids.
  • In the citric cycle and oxidative phosphorylation, the acetyl group of acetyl-CoA is oxidized to carbon dioxide (CO2 ) and water ( H2O).The acetyl CoA can also be used to synthesize ketone body and fatty acids.

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