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Chapter 20: Q39P (page 717)

Calculate the cost, in ATP equivalents, of converting 12 acetyl-CoA to lignocerate(a C24fatty acid; Table 9-1) when elongation occurs in the mitochondrion

Short Answer

Expert verified

The cost of converting 12 acetyl-CoA to lignocerate, in ATP equivalents, when elongation occurs in the mitochondrion, is a total of 62 ATP consumed

Step by step solution

01

Definition of Palmitate

Palmitate is a C16 saturated fatty acid that requires a total of 7 rounds of -oxidation to yield 8 acetyl-CoA molecules.Acetyl-CoA is then transferred to be used in the citric acid cycle to yield a sufficient amount of ATP.

02

ATP in palmitate synthesis

Palmitate synthesis consumes a total of 7 A T P and 14NADPH (1NADPH = 2.5ATP, which is equivalent to (14脳2.5) ATP = 35ATP).

03

ATP in lignocerate synthesis in mitochondria

When 4 more 2-carbon units as acetyl-CoA in the mitochondria are added to palmitate to produce lignocerate, this consumes a total of:

1., which is equivalent to (4脳2.5)础罢笔=10础罢笔)

2.which is equivalent to (4脳2.5)础罢笔=10础罢笔).

Therefore, this would give a total of (7+35+10+10)ATP=62ATPconsumed.

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Answer

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