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Chapter 20: Q17CP (page 697)
Question:What is the role of ATP-citrate lyase in fatty acid synthesis?
ATP-citrate lyase is an enzyme used for the conversion of citrate in the cytosol to acetyl-CoA and oxaloacetate.
Acetyl-CoA can be used for fatty acid biosynthesis.
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What do familial hypercholesterolemia and Tangier disease reveal about the development of atherosclerosis?
a) What is the charge of bile acids in the small intestine, where
the pH is ?
(b) According to one hypothesis, bile acids are toxic to bacteria and so could help limit their growth in the intestine. Propose amechanism for this bactericidal activity
Question:How do cytosolic acyl groups enter the mitochondrion for degradation?
Two lipoproteins have the following characteristics:
Diameter (A) % | Triacylglycerol % | Protein | |
Lipoprotein A | 200 | 10 | 20 |
Lipoprotein B | 100 | 5 | 55 |
Which lipoprotein has a higher density?
Why are the symptoms of carnitine palmitoyl transferase|| deficiency more severe during fasting?
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