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Chapter 16: Q8CP (page 536)

Describe the role of glycogenin.

Short Answer

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Answer:

Glycogenin helps in the synthesis of glycogen. The glycogen chain is to be extended from a primer built by the protein glycogenin.

Step by step solution

01

Definition of Glycogenin

Glycogenin is known to be a homodimer of 37-kDa subunits. This enzyme is classified as a glycosyltransferase

02

Glycogenin reaction

Glycogeninacts is a glycosyltransferase which attaches a glucose residue to the OH group of its Tyr 194. This enzyme later helps extend the glucose chain by up to seven additional residues, which will help form a glycogen primer. The glucose residues are donated by UDPG (uridinedisphophoglucose).

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Most popular questions from this chapter

Compare the synthesis of O- and N-linked oligosaccharides

Summarize the effects of phosphorylation and dephosphorylation on glycogen phosphorylase and glycogen synthase.

In the Cori cycle, the lactate product of glycolysis in muscle is trans-formed back into glucose by the liver.

(a) List the enzymes involved in the lactate 鈫� glucose pathway.

(b) What is the net gain/loss of ATP for one round of the Cori cycle (glucose 鈫� lactate 鈫� glucose)?

Explain why the glycogen phosphorylase reaction (螖G掳鈥�=3.1 kJ 路 mol鈭�1) is exergonic in the cell.

Describe the reactions of gluconeogenesis. Which reactions are not shared with glycolysis?
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