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Chapter 8: Q10P (page 221)

Nearly all enzymes that require a nicotinamide cofactor use either NAD+/NADH or NADP+/NADPH (Figure 11-3) but not both. Compare the net charge of each cofactor.

Short Answer

Expert verified

The charges of NAD+/NADHare +1/0and NADP+/NADPHare -1/-2.

Step by step solution

01

Enzymes

Enzyme, a molecule that works as a catalyst in living organisms, controlling the pace at which chemical processes take place without changing itself.

02

Explanation

Since the hydrogen in the nicotinamide ring is uncharged, NAD+ has a net charge of +1, while NADHhas a net charge of zero. The phosphate group in NADP+has a net charge of -1and NADPHhas a negative net charge of -2.

Reduced forms

Hence, they have different charges.

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