Q29P Phosphatidylethanolamine and PIP... [FREE SOLUTION]

Chapter 13: Q29P (page 441)

Phosphatidylethanolamine and PIP2 containing identical fatty acyl residues can be hydrolyzed with the same efficiency by a certain phospholipase C. Will the hydrolysis products of the two lipids have the same effect on protein kinase C? Explain.

Short Answer

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Protein kinase C will not be affected by hydrolysis products.

Step by step solution

Explanation of Concept

The phospholipid class phosphatidylethanolamine is found in biological membranes. The addition of cytidine diphosphate-ethanolamine to diglycerides results in the formation of cytidine monophosphate.

Step 2:Effecting on Protein Kinase

Both Phosphatidylethonolamine and ${PIP}_{2}$ which contain the same fatty acyl, will break on the glycero-phospho link, resulting in DAG in both situations.

Despite the fact that both molecules create DAG, phosphatidylethonolamine does not produce the second messenger ${IP}_{3}$ Without ${IP}_{3} {Ca}^{2+}$ the protein kinase $C$ will not be released, causing the activity of $C$ to be altered.

Therefore, Protein kinase $C$ will not be affected by hydrolysis products.

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91影视

Phosphatidylethanolamine and PIP2 containing identical fatty acyl residues can be hydrolyzed with the same efficiency by a certain phospholipase C. Will the hydrolysis products of the two lipids have the same effect on protein kinase C? Explain.

Short Answer

Step by step solution

Explanation of Concept

Step 2:Effecting on Protein Kinase

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