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Chapter 37: Q9. (page 1078)

When insulin binds to its receptor, the complex is
endocytosed into the cell. This is an example of ______ in
response to hormone signaling.
a. cAMP activation
b. generating an intracellular receptor
c. activation of a hormone response element
d. receptor down-regulation

Short Answer

Expert verified

When insulin binds to its receptor, the complex gets
endocytosed or enters the cell. This is an example of receptor down-regulation in response to hormone signaling. The correct option is d.

Step by step solution

01

Step 1. Introduction 

Downregulation is the process by which a cell responds to an external stimulus by producing less of a biological component, such as RNA or protein in the cell. So here, receptor down-regulation is observed.

02

Step 2. Explanation of the correct option 

Receptor downregulation is defined by a reduction in the overall number of receptors in the cell as a result of endocytosis and subsequent receptor degradation brought on by repeated exposure to agonists.

03

Step 3. Explanation of the incorrect options 

cAMP functions by triggering protein kinase A. (PKA, cAMP-dependent protein kinase)

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