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Chapter 10: Q. 42 (page 278)

List the regulatory mechanisms that might be lost in a

cell producing faulty p53.

Short Answer

Expert verified

(a.) Damaged DNA monitoring.

(b.) Apoptosis triggering

(c.) Recruitment of repair enzymes

Step by step solution

01

Step 1. Introduction

p53 is a gene that controls the cell division and cell death.

02

Step 2. Explanation

Mutation in p53 gene causes loss of monitoring of quality of DNA, trigger apoptosis and recruitment of repair enzymes.

These changes in a cell due to faulty p53 causes cancer due to continuous cell division.

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Most popular questions from this chapter

A gene that codes for a positive cell-cycle regulator is called a(n) _____.

a. kinase inhibitor.

b. tumor suppressor gene.

c. proto-oncogene.

d. oncogene.

Which negative regulatory molecule can trigger cell suicide (apoptosis) if vital cell cycle events do not occur?

a. p53

b. p21

c. retinoblastoma protein (Rb)

d. cyclin-dependent kinase (Cdk)

___________ are changes to the order of nucleotides in a segment of DNA that codes for a protein.

a. Proto-oncogenes

b. Tumor suppressor genes

c. Gene mutations

d. Negative regulators

Identical copies of chromatin held together by cohesin at the centromere are called _____.

a. histones.

b. nucleosomes.

c. chromatin.

d. sister chromatids.

Which eukaryotic cell-cycle event is missing in binary fission?

a. cell growth

b. DNA duplication

c. karyokinesis

d. cytokinesis
See all solutions

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