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Chapter 10: Q. 42 (page 278)

List the regulatory mechanisms that might be lost in a

cell producing faulty p53.

Short Answer

Expert verified

(a.) Damaged DNA monitoring.

(b.) Apoptosis triggering

(c.) Recruitment of repair enzymes

Step by step solution

01

Step 1. Introduction

p53 is a gene that controls the cell division and cell death.

02

Step 2. Explanation

Mutation in p53 gene causes loss of monitoring of quality of DNA, trigger apoptosis and recruitment of repair enzymes.

These changes in a cell due to faulty p53 causes cancer due to continuous cell division.

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Most popular questions from this chapter

What is the main prerequisite for clearance at the G2 checkpoint?

a. cell has reached a sufficient size

b. an adequate stockpile of nucleotides

c. accurate and complete DNA replication

d. proper attachment of mitotic spindle fibres to kinetochores

Describe how the duplicated bacterial chromosomes are distributed into new daughter cells without the direction of the mitotic spindle.

Describe the general conditions that must be met at each of the three main cell-cycle checkpoints.

Explain the difference between a proto-oncogene and a tumor-suppressor gene.

Separation of the sister chromatids is a characteristic of which stage of mitosis?

a. prometaphase

b. metaphase

c. anaphase

d. telophase
See all solutions

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