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Chapter 9: Q. 32 (page 252)

How does the extracellular matrix control the growth of cells?

Short Answer

Expert verified

If receptors are not in touch with the cell, appropriate functioning will not occur, leading to cell death.

Step by step solution

01

Step. 1 Introduction 

The extracellular matrix seems to be a complex web of functional and structural proteins that are built within tissue-specific patterns.

02

Step. 2 Explanation 

To receive positive signals that allow the cell to exist, receptors upon that cell surface must be in touch with the extracellular matrix. The cell will die if the receptors are not activated by binding. This ensures that cells remain in the right area in the body and helps to avoid invasive cell development, which happens during cancer metastasis.

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Most popular questions from this chapter

How does NF-魏B induce gene expression?

a. A small, hydrophobic ligand binds to NF-魏B, activating it.

b. Phosphorylation of the inhibitor I魏-B dissociates the complex between it and NF-魏B, and allows NF- 魏B to enter the nucleus and stimulate transcription.

c. NF-魏B is phosphorylated and is then free to enter the nucleus and bind DNA.

d. NF-魏B is a kinase that phosphorylates a transcription factor that binds DNA and promotes protein production.

What is the difference between intracellular signaling and intercellular signaling?

How are the effects of paracrine signaling limited to an area near the signaling cells?

Where do DAG and IP3 originate?

a. They are formed by phosphorylation of cAMP.

b. They are ligands expressed by signaling cells.

c. They are hormones that diffuse through the plasma

membrane to stimulate protein production.

d. They are the cleavage products of the inositol phospholipid, PIP2.

A scientist notices that when she adds a small, water soluble molecule to a dish of cells, the cells turn off transcription of a gene. She hypothesizes that the ligand she added binds to a(n) ______ receptor.

a. Intracellular

b. Hormone

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