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Chapter 13: Problem 9

Would you classify NMDA receptors as ionotropic or metabotropic? Why?

Short Answer

Expert verified
NMDA receptors are classified as ionotropic receptors. They function as ligand-gated ion channels which open up to allow ion flow upon ligand binding, which is a characteristic of ionotropic receptors, not metabotropic receptors.

Step by step solution

01

Understanding NMDA receptors

N-methyl-D-aspartate (NMDA) receptors are a type of glutamate receptor. They are permeable to cations, such as calcium ions, and play a key role in synaptic plasticity, memory function, and neuronal development.
02

Classifying NMDA receptors

NMDA receptors are recognized as ligand-gated ion channels. This is because upon binding of the ligand (glutamate), they open an ion channel that allows specific ions (primarily calcium) to pass through the cell membrane. This quick response characterizes ionotropic receptors.
03

Conclusion

Based on the characteristics of NMDA receptors, being ligand-gated ion channels that allow ion flow upon ligand binding, we can conclude that they belong to the category of ionotropic receptors.

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