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Quit smoking Nicotine patches are often used to help smokers quit. Does giving medicine to fight depression help? A randomized double-blind experiment assigned 244smokers to receive nicotine patches and another 245to receive both a patch and the antidepressant drug bupropion. After a year, 40subjects in the nicotine patch group had abstained from smoking, as had 87in the patch-plus-drug group. Construct and interpret a 99%confidence interval for the difference in the true proportion of smokers like these who would abstain when using bupropion and a nicotine patch and the proportion who would abstain when using only a patch.

Short Answer

Expert verified

Confidence Interval is(-0.2908,-0.0916).

Step by step solution

01

Given Information

It is given that x1=40

x2=87

n1=244

n2=245

c=99%=0.99

02

Checking the conditions

Random: Samples are independent random samples.

Independent: 224<10%of all smokers.

Normal: The success are 40,87and failures are 204,158which are greater than ten. So, is satisfied.

03

Calculations

Sample Proportion: p^1=x1n1=40244=0.1639

and p^2=x2n2=87245=0.3551

For 1-=0.99, value of role="math" localid="1654639742329" z/2=z0.005using table is

za/2=2.575

Hence, confidence interval is p^1-p^2-za/2p^11-p^1n1+p^21-p^2n2

=(0.1639-0.3551)-2.5750.1639(1-0.1639)244+0.3551(1-0.3551)245

-0.2908

and p^1-p^2+za/2p^11-p^1n1+p^21-p^2n2

=(0.1639-0.3551)+2.5750.1639(1-0.1639)244+0.3551(1-0.3551)245

-0.0916

Hence, confidence interval is(-0.2908,-0.0916)

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