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Researchers in Japan conducted an experiment on 13 individuals who were extremely allergic to poison ivy. On one arm, each subject was rubbed with a poison ivy leaf and told the leaf was harmless. On the other arm, each subject was rubbed with a harmless leaf and told it was poison ivy. All the subjects developed a rash on the arm where the harmless leaf was rubbed. Of the 13 subjects, 11 did not have any reaction to the real poison ivy leaf.\(^{39}\) (a) What was the placebo in this experiment? (b) Explain how the results of this study support the idea of a placebo effect.

Short Answer

Expert verified
(a) The placebo was the harmless leaf. (b) The subjects developed a rash from the harmless leaf, showing their belief, not the actual exposure, caused the reaction.

Step by step solution

01

Identify the Placebo

A placebo is a substance or treatment with no therapeutic effect that is used as a control in testing new drugs. In this experiment, the placebo was the harmless leaf that subjects were told was poison ivy.
02

Explain the Purpose of the Placebo

The harmless leaf, which was the placebo in the experiment, served the purpose of testing whether the belief in exposure to poison ivy could induce a physical reaction. This helps illustrate the placebo effect, where an individual experiences a real change in symptoms due to their belief in the treatment.
03

Analyze the Experiment Results

Out of the 13 subjects, all developed a rash on the arm rubbed with the harmless leaf, which they believed to be poison ivy. This indicates that the subjects had a psychological reaction based on their belief and not the actual substance, demonstrating the placebo effect. On the other hand, 11 out of 13 did not react to the real poison ivy when they were told it was harmless.
04

Conclusion on the Placebo Effect

The results support the idea of a placebo effect as the belief in being exposed to poison ivy caused a physical reaction even when there was no harmful exposure. The harmless leaf acting as a placebo led to a rash based solely on the subjects’ expectations.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Psychological Reaction
Our minds are powerful, and the psychological reaction can significantly influence our physical state. In the experiment with poison ivy and a harmless leaf, the participants experienced a psychological response based on what they believed. Even though the harmless leaf could not cause an allergic reaction, the mere suggestion that it was poison ivy was enough to trigger a rash.
This reaction highlights how our beliefs can affect how our body responds, showing how deeply intertwined our mental state is with our physical reactions. This connection between mind and body is why the placebo effect is such a fascinating topic in psychology and medicine. Researchers study these reactions to understand better how beliefs can alter physiological outcomes.
Experiment Results
The results from the experiment are compelling. Each participant developed a rash on the arm where the harmless leaf was applied because they believed it was poison ivy. However, when the real poison ivy was applied, only 2 out of 13 participants showed an allergic reaction, despite their high sensitivity to the plant.
These results clearly illustrate the power of belief and expectation. It demonstrates that the rash was not due to the physical properties of the leaves, but rather a result of the participants' beliefs. Such findings are crucial in exploring the placebo effect since they shed light on the psychological influence over physical responses.
Control Treatment
A control treatment in experiments serves as a benchmark to compare the effects of a variable being tested. In this case, the harmless leaf, when presented as poison ivy, served as the control treatment.
By comparing reactions to the placebo leaf versus the real poison ivy, researchers can see the effect of the psychological suggestion alone. The experiment concluded that expectations could influence physical symptoms, as most participants only reacted to what they believed was poison ivy, despite no actual exposure to the allergen.
  • This highlighted that the control setup was essential for isolating and understanding the psychological component involved in the reactions.
  • Without a control treatment, it would be difficult to determine if the real rash was due to the allergen or the suggestion of one.
Allergic Reaction
An allergic reaction is a hypersensitive response by the immune system to a substance that is typically harmless to most people. In this experiment, participants were known to have strong allergic reactions to poison ivy. However, most did not react to the real poison ivy when they thought it was harmless.
On the other hand, they developed a rash from the harmless leaf due to their belief that it was poison ivy.
  • The difference in reactions underscores the role of the mind in allergy symptoms, indicating that psychological factors can trigger similar symptoms to those caused by a real allergen.
  • This has implications for understanding how psychological conditions might exacerbate allergy symptoms and how treatments can address both physical and psychological components.
Understanding allergic reactions from a psychological perspective is becoming increasingly important in medical science.

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Most popular questions from this chapter

A group of students wants to perform an experiment to determine whether Brand A or Brand B deodorant lasts longer. One group member suggests the following design: Recruit 40 student volunteers—20 male and 20 female. Separate by gender, since male and female bodies might respond differently to deodorant. Give all the males Brand A deodorant and all the females Brand B. Have each student rate how well the deodorant is still working at the end of the school day on a 0 to 10 scale. Then compare ratings for the two treatments. (a) Identify any flaws you see in the proposed design for this experiment. (b) Describe how you would design the experiment. Explain how your design addresses each of the problems you identified in (a).

Cardiologists at Athens Medical School in Greece wanted to test whether chocolate affected blood flow in the blood vessels. The researchers recruited 17 healthy young volunteers, who were each given a 3.5-ounce bar of dark chocolate, either bittersweet or fake chocolate. On another day, the volunteers were switched. The subjects had no chocolate outside the study, and investigators didn’t know whether a subject had eaten the real or the fake chocolate. An ultrasound was taken of each volunteer’s upper arm to see the functioning of the cells in the walls of the main artery. The investigators found that blood vessel function was improved when the subjects ate bittersweet chocolate, and that there were no such changes when they ate the placebo (fake chocolate).\(^{45}\) (a) What type of design did the investigators use in their study? (b) Explain why the investigators chose this design instead of a completely randomized design. (c) Why is it important to randomly assign the order of the treatments for the subjects?

A biologist would like to determine which of two brands of weed killer is less likely to harm the plants in a garden at the university. Before spraying near the plants, the biologist decides to conduct an experiment using 24 individual plants. Which of the following two plans for randomly assigning the treatments should the biologist use? Why? Plan A: Choose the 12 healthiest-looking plants. Apply Brand X weed killer to all 12 of those plants. Apply Brand Y weed killer to the remaining 12 plants. Plan B: Choose 12 of the 24 plants at random. Apply Brand X weed killer to those 12 plants and Brand Y weed killer to the remaining 12 plants.

Select the best answer A report in a medical journal notes that the risk of developing Alzheimer’s disease among subjects who (voluntarily) regularly took the anti-inflammatory drug ibuprofen (the active ingredient in Advil) was about half the risk among those who did not. Is this good evidence that ibuprofen is effective in preventing Alzheimer’s disease? (a) Yes, because the study was a randomized, comparative experiment. (b) No, because the effect of ibuprofen is confounded with the placebo effect. (c) Yes, because the results were published in a reputable professional journal. (d) No, because this is an observational study. An experiment would be needed to confirm (or not confirm) the observed effect. (e) Yes, because a 50% reduction can’t happen just by chance.

A high school’s student newspaper plans to survey local businesses about the importance of students as customers. From telephone book listings, the newspaper staff chooses 150 businesses at random. Of these, 73 return the questionnaire mailed by the staff. Identify the population and the sample.

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