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If \(X\) is a Poisson variable with mean \(\mu=\exp \left(x^{\mathrm{T}} \beta\right)\) and \(Y\) is a binary variable indicating the event \(X>0\), find the link function between \(\mathrm{E}(Y)\) and \(x^{\mathrm{T}} \beta\).

Short Answer

Expert verified
The link function is \(\mathrm{E}(Y) = 1 - e^{-\exp(x^T \beta)}\).

Step by step solution

01

Define the Poisson Variable

The variable \(X\) follows a Poisson distribution with mean \(\mu = \exp(x^T \beta)\). This is the key characteristic of the distribution that will help us relate \(Y\) to the parameters of the Poisson variable.
02

Define the Binary Variable Y

The binary variable \(Y\) represents whether the Poisson variable \(X\) is greater than zero, i.e., \(Y = 1\) if \(X > 0\), and \(Y = 0\) if \(X = 0\). Our goal is to establish a connection between \(\mathrm{E}(Y)\) and \(x^T \beta\).
03

Use the Complement of Probability

Since \(Y = 1\) if \(X > 0\), \(P(Y = 1) = P(X > 0)\). We know \(P(X = 0) = e^{-\mu}\) from the properties of a Poisson distribution. Therefore, \[ P(X > 0) = 1 - P(X = 0) = 1 - e^{-\mu}. \]
04

Substitute the Mean

Substitute \(\mu = \exp(x^T \beta)\) into the probability expression we found: \[ P(X > 0) = 1 - e^{-\exp(x^T \beta)}. \]
05

Identify the Link Function

The link function relates \(\mathrm{E}(Y)\) to \(x^T \beta\). We found that \[ \mathrm{E}(Y) = P(Y = 1) = 1 - e^{-\exp(x^T \beta)}. \] This is the link function between \(\mathrm{E}(Y)\) and \(x^T \beta\).

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Link Function
A link function is a powerful tool used to connect the linear predictor of a model, often denoted as \(x^T \beta\), to the expected value of the outcome variable. In Poisson regression, link functions help to relate the mean of the Poisson-distributed outcome to the covariates.
Every distribution has its own canonical link function that matches best with its characteristics, and for the Poisson distribution, this is the log link function.
The Poisson distribution is unique because its mean is an exponential function of the linear predictor. This is where the exponential mean function comes into play.
The log link function specifically is defined as \(\log(\mu) = x^T \beta\), which rearranges as : \(\mu = \exp(x^T \beta)\). This ensures that the mean is always positive, which is a requirement for Poisson-distributed outcomes.
When our outcome is a binary variable \(Y\), representing whether a Poisson variable \(X\) is greater than zero, the link function becomes important to relate \(\mathrm{E}(Y)\) to \(x^T \beta\). By substituting \(\mu\) with \(\exp(x^T \beta)\) in the formula for \(\mathrm{E}(Y)\), we derive a connection: \(\mathrm{E}(Y) = 1 - e^{-\exp(x^T \beta)}\). This derived formula is another form of link function used specifically in this binary context where \(X\) is Poisson-distributed.
Binary Variable
Binary variables are extremely common in statistical modeling and represent two possible outcomes. In the exercise, \(Y\) is an example of a binary variable, where it indicates the event of \(X > 0\).
More concretely, a binary variable takes on the values 1 or 0. These values make binary variables ideal for representing outcomes such as "yes/no", "success/failure", or "occurred/did not occur" events.
In the context of Poisson regression, binary variables can often indicate whether an event has crossed a certain threshold—like whether a count is positive or zero.
Our goal for a binary variable like \(Y\) is to establish a meaningful relationship between its expected value and the linear predictor \(x^T \beta\).
To achieve this, we examine probabilities relating to the event in question. We know that \(P(Y = 1) = P(X > 0)\), and by using the properties of the Poisson distribution, we found \(P(X > 0) = 1 - e^{-\mu}\). After substituting the expression for \(\mu\), this becomes \(1 - e^{-\exp(x^T \beta)}\). Thus, we can seamlessly tie the occurrence of the event "\(X > 0\)" to the underlying predictors.
Exponential Mean Function
The exponential mean function is pivotal in understanding the structure of a Poisson regression. In mathematical terms, the mean \(\mu\) of a Poisson-distributed variable \(X\) can be expressed as \(\mu = \exp(x^T \beta)\).
This function ensures that whatever the combination of predictors (via \(x^T \beta\)), the resulting mean is always positive, aligning perfectly with the requirement of a Poisson distribution.
The exponential nature of the function implies that each unit change in the linear component \(x^T \beta\) results in a multiplicative change in the expected count \(\mu\). Rather than adding or subtracting from the count directly, this model respects counting properties.
In the exercise, this concept was used in conjunction with a binary indicator \(Y\). By substituting the exponential expression for \(\mu\) into the link function formula for calculating \(\mathrm{E}(Y)\), we highlighted its utility in determining the probability of non-zero count events \(Y = 1\).
This linkage reveals the intrinsic capability of the exponential mean function to smoothly convert linear combinations into probabilities—describing real-world events quite effectively with the Poisson regression framework.

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Most popular questions from this chapter

Let \(Y_{1}, \ldots, Y_{n}\) be independent exponential variables with hazards \(\lambda_{j}=\exp \left(\beta^{\mathrm{T}} x_{j}\right)\). (a) Show that the expected information for \(\beta\) is \(X^{\mathrm{T}} X\), in the usual notation. (b) Now suppose that \(Y_{j}\) is subject to uninformative right censoring at time \(c_{j}\), so that \(y_{j}\) is a censoring time or a failure time as the case may be. Show that the log likelihood is $$ \ell_{U}(\beta)=\sum_{f} \beta^{\mathrm{T}} x_{j}-\sum_{j=1}^{n} \exp \left(\beta^{\mathrm{T}} x_{j}\right) y_{j} $$ where \(\sum_{f}\) denotes a sum over observations seen to fail. If the \(j\) th censoring-time is exponentially distributed with rate \(\kappa_{j}\), show that the expected information for \(\beta\) is \(X^{\mathrm{T}} X-\) \(X^{\mathrm{T}} C X\), where \(C=\operatorname{diag}\left\\{c_{1}, \ldots, c_{n}\right\\}\), and \(c_{j}=\kappa_{j} /\left(\kappa_{j}+\lambda_{j}\right)\) is the probability that the \(j\) th observation is censored. What is the implication for estimation of \(\beta\) if the \(c_{j}\) are constant? (c) Sometimes a variable \(W_{j}\) has been measured which can act as a surrogate response variable for censored individuals. We formulate this as \(W_{j}=Z_{j} / U_{j}\), where \(Z_{j}\) is the unobserved remaining life-time of the \(j\) th individual from the moment of censoring, and \(U_{j}\) is a noise component which has a fixed distribution independent of the censoring time and of \(x_{j}\). Owing to the exponential assumption, the excess life \(Z_{j}\) is independent of \(Y_{j}\) if censoring occurred. If \(U_{j}\) has gamma density $$ \alpha^{K} u^{\kappa-1} \exp (-\alpha u) / \Gamma(\kappa), \quad \alpha, \kappa>0, u>0 $$ show that \(W_{j}\) has density $$ \lambda_{j} \kappa \alpha^{\kappa} /\left(\alpha+\lambda_{j} w\right)^{\kappa+1}, \quad w>0 $$ Show that the log likelihood for the data, including the additional information in the \(W_{j}\), is $$ \ell(\beta)=L_{U}(\beta)+\sum_{c}\left\\{\beta^{\mathrm{T}} x_{j}+\log \kappa+\kappa \log \alpha-(\kappa+1) \log \left(\alpha+e^{\beta^{\mathrm{T}}} x_{j} w_{j}\right)\right\\} $$ where \(\sum_{c}\) denotes a sum over censored individuals, and we have assumed that \(\alpha\) and \(\kappa\) are known. Show that the expected information for \(\beta\) is $$ X^{\mathrm{T}} X-2 /(\kappa+2) X^{\mathrm{T}} C X $$ and compare this with (b). Explain qualitatively in terms of the variability of the distribution of \(U\) why the loss of information decreases as \(\kappa\) increases. \((\operatorname{Cox}, 1983)\)

A positive stable random variable \(U\) has \(\mathrm{E}\left(e^{-s U}\right)=\exp \left(-\delta s^{\alpha} / \alpha\right), 0<\alpha \leq 1\) (a) Show that if \(Y\) follows a proportional hazards model with cumulative hazard function \(u \exp \left(x^{\mathrm{T}} \beta\right) H_{0}(y)\), conditional on \(U=u\), then \(Y\) also follows a proportional hazards model unconditionally. Are \(\beta, \alpha\), and \(\delta\) estimable from data with single individuals only? (b) Consider a shared frailty model, as in the previous question, with positive stable \(U\). Show that the joint survivor function may be written as $$ \mathcal{F}\left(y_{1}, y_{2}\right)=\exp \left(-\left[\left\\{-\log \mathcal{F}_{1}\left(y_{1}\right)\right\\}^{1 / \alpha}+\left\\{-\log \mathcal{F}_{2}\left(y_{2}\right)\right\\}^{1 / \alpha}\right]^{\alpha}\right), \quad y_{1}, y_{2}>0 $$ in terms of the marginal survivor functions \(\mathcal{F}_{1}\) and \(\mathcal{F}_{2}\). Show that if the conditional cumulative hazard functions are Weibull, \(u H_{r}(y)=u \xi_{r} y^{\gamma}, \gamma>0, r=1,2\), then the marginal survivor functions are also Weibull. Show also that the time to the first event has a Weibull distribution.

Consider independent exponential variables \(Y_{j}\) with densities \(\lambda_{j} \exp \left(-\lambda_{j} y_{j}\right)\), where \(\lambda_{j}=\) \(\exp \left(\beta_{0}+\beta_{1} x_{j}\right), j=1, \ldots, n\), where \(x_{j}\) is scalar and \(\sum x_{j}=0\) without loss of generality. (a) Find the expected information for \(\beta_{0}, \beta_{1}\) and show that the maximum likelihood estimator \(\widehat{\beta}_{1}\) has asymptotic variance \(\left(n m_{2}\right)^{-1}\), where \(m_{2}=n^{-1} \sum x_{j}^{2}\) (b) Under no censoring, show that the partial log likelihood for \(\beta_{1}\) equals $$ -\sum_{j=1}^{n} \log \left\\{\sum_{i=j}^{n} \exp \left(\beta_{1} x_{(i)}\right)\right\\} $$ where the elements of the rank statistic \(R=\\{(1), \ldots,(n)\\}\) are determined by the ordering on the failure times, \(y_{(1)}<\cdots

Let \(Y\) be a positive continuous random variable with survivor and hazard functions \(\mathcal{F}(y)\) and \(h(y)\). Let \(\psi(x)\) and \(\chi(x)\) be arbitrary continuous positive functions of the covariate \(x\), with \(\psi(0)=\chi(0)=1\). In a proportional hazards model, the effect of a non-zero covariate is that the hazard function becomes \(h(y) \psi(x)\), whereas in an accelerated life model, the survivor function becomes \(\mathcal{F}\\{y \chi(x)\\}\). Show that the survivor function for the proportional hazards model is \(\mathcal{F}(y)^{\psi(x)}\), and deduce that this model is also an accelerated life model if and only if $$ \log \psi(x)+G(\tau)=G\\{\tau+\log \chi(x)\\} $$ where \(G(\tau)=\log \left\\{-\log \mathcal{F}\left(e^{\tau}\right)\right\\}\). Show that if this holds for all \(\tau\) and some non-unit \(\chi(x)\), we must have \(G(\tau)=\kappa \tau+\alpha\), for constants \(\kappa\) and \(\alpha\), and find an expression for \(\chi(x)\) in terms of \(\psi(x) .\) Hence or otherwise show that the classes of proportional hazards and accelerated life models coincide if and only if \(Y\) has a Weibull distribution.

Two individuals with cumulative hazard functions \(u H_{1}\left(y_{1}\right)\) and \(u H_{2}\left(y_{2}\right)\) are independent conditional on the value \(u\) of a frailty \(U\) whose density is \(f(u)\) (a) For this shared frailty model, show that $$ \mathcal{F}\left(y_{1}, y_{2}\right)=\operatorname{Pr}\left(Y_{1}>y_{1}, Y_{2}>y_{2}\right)=\int_{0}^{\infty} \exp \left\\{-u H_{1}\left(y_{1}\right)-u H_{2}\left(y_{2}\right)\right\\} f(u) d u $$ If \(f(u)=\lambda^{\alpha} u^{\alpha-1} \exp (-\lambda u) / \Gamma(\alpha)\), for \(u>0\) is a gamma density, then show that $$ \mathcal{F}\left(y_{1}, y_{2}\right)=\frac{\lambda^{\alpha}}{\left\\{\lambda+H_{1}\left(y_{1}\right)+H_{2}\left(y_{2}\right)\right\\}^{\alpha}}, \quad y_{1}, y_{2}>0 $$ and deduce that in terms of the marginal survivor functions \(\mathcal{F}_{1}\left(y_{1}\right)\) and \(\mathcal{F}_{2}\left(y_{2}\right)\) of \(Y_{1}\) and \(Y_{2}\) $$ \mathcal{F}\left(y_{1}, y_{2}\right)=\left\\{\mathcal{F}_{1}\left(y_{1}\right)^{-1 / \alpha}+\mathcal{F}_{2}\left(y_{2}\right)^{-1 / \alpha}-1\right\\}^{-\alpha}, \quad y_{1}, y_{2}>0 $$ What happens to this joint survivor function as \(\alpha \rightarrow \infty\) ? (b) Find the likelihood contributions when both individuals are observed to fail, when one is censored, and when both are censored. (c) Extend this to \(k\) individuals with parametric regression models for survival.

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