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Obesity is an important determinant of cardiovascular disease because it directly affects several established cardiovascular risk factors, including hypertension and diabetes. It is estimated that the average weight for an 18 -year-old woman is 123 lbs. and increases to 142 lbs. at 50 years of age. Also, let us assume that the average SBP for a 50-year-old woman is \(125 \mathrm{mm}\) Hg, with a standard deviation of \(15 \mathrm{mm} \mathrm{Hg},\) and that \(\mathrm{SBP}\) is normally distributed. What proportion of 50-year-old women is hypertensive, if hypertension is defined as \(\mathrm{SBP} \geq 140 \mathrm{mm}\) Hg?

Short Answer

Expert verified
About 15.87% of 50-year-old women have hypertension (SBP ≥ 140 mm Hg).

Step by step solution

01

Understand the Problem

We need to find the proportion of 50-year-old women who have systolic blood pressure (SBP) greater than or equal to 140 mm Hg. This problem assumes a normal distribution of SBP with a mean of 125 mm Hg and a standard deviation of 15 mm Hg.
02

Standardize the Variable

To find the proportion of women with SBP ≥ 140 mm Hg, we first convert 140 mm Hg to a z-score using the formula: \[ z = \frac{X - \mu}{\sigma} \]where \(X = 140\), \(\mu = 125\), and \(\sigma = 15\). This gives us: \[ z = \frac{140 - 125}{15} = \frac{15}{15} = 1 \].
03

Use the Standard Normal Distribution

Using the z-score value of 1, we consult standard normal distribution tables or use a calculator to find the area to the right of z = 1 in the standard normal distribution curve. This gives us the proportion of women who have a SBP ≥ 140 mm Hg.
04

Interpret the Result

The area to the right of z = 1 is approximately 0.1587. This means 15.87% of 50-year-old women are hypertensive, with an SBP ≥ 140 mm Hg.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Cardiovascular Disease
Cardiovascular diseases (CVDs) are a group of disorders affecting the heart and blood vessels. These diseases are a leading cause of illness and death worldwide. For instance, coronary artery disease, heart attacks, and strokes are some of the common forms of cardiovascular disease. Obesity is considered a major risk factor for CVDs alongside other factors like hypertension, high cholesterol, and diabetes.

Obesity leads to an increase in blood pressure, putting extra strain on the heart and blood vessels. This scenario can lead to a condition called hypertension, where the blood pressure in the arteries is persistently elevated. Understanding the link between factors like obesity and cardiovascular disease is crucial for prevention and management. By addressing risk factors early, individuals can reduce their risk of developing cardiovascular disease.
Normal Distribution
Normal distribution is a statistical concept used to describe how traits or variables are distributed in a population. Often called the "bell curve" because of its shape, it shows that most individuals in a population will have values around a central peak.

For many biological traits, such as height, weight, or systolic blood pressure (SBP), the values in a normal distribution will taper off symmetrically on both sides of the mean. This means fewer individuals fall at the extreme low or high ends. In the exercise about women's SBP, a normal distribution with a mean of 125 mm Hg helps us understand where most women's SBP levels fall, and how many might fall beyond 140 mm Hg, or become hypertensive.
Z-Score
A z-score is a statistical measurement that tells us how many standard deviations a data point, like a person's SBP, is from the mean. It's a way of standardizing scores so that different data can be compared on a common scale.

The formula to find a z-score is: \[ z = \frac{X - \mu}{\sigma} \]where:
  • \(X\) is the value you're examining,
  • \(\mu\) is the mean,
  • \(\sigma\) is the standard deviation.
In our exercise, we used a z-score to find how many standard deviations the SBP level of 140 mm Hg is from the mean of 125 mm Hg. By finding a z-score of 1, we concluded that a 140 mm Hg falls 1 standard deviation above the average.
Standard Deviation
Standard deviation is a statistical measure that shows the amount of variation or dispersion in a set of values. A small standard deviation indicates that the values tend to be close to the mean, whereas a large standard deviation indicates that the values are spread out over a wider range.

In the context of our exercise with the SBP levels of 50-year-old women, the standard deviation was given as 15 mm Hg. This means that most women's systolic blood pressures are within 15 mm Hg above or below the average SBP of 125 mm Hg. Understanding standard deviation helps in predicting the spread of data points. It provides insight into how individual measurements can differ from the average value in a normal distribution.

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Most popular questions from this chapter

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