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Chapter 1: Problem 58

Writing: Strokes People who have had strokes are often put on "blood thinners" such as aspirin or Coumadin to help prevent a second stroke. Describe the design of a controlled experiment to determine whether aspirin or Coumadin works better in preventing second strokes. Assume you have 300 people who have had a first stroke to work with. Include all the features of a good experiment. Also decide how the results would be determined.

Short Answer

Expert verified
The experiment can be designed by first splitting the 300 patients into two groups with 150 each. Give one group aspirin and another Coumadin. Carry out the experiment by implementing a double-blind procedure. Analyze the results by comparing how many from each group had a second stroke to determine which medication is more effective in preventing second strokes.

Step by step solution

01

Identify Variables

First, identify the independent and dependent variables. The independent variable is the type of medication a patient is given(Assume that they are equally distributed into two groups: one group is given aspirin, and the other is given Coumadin). The dependent variable is whether the patient has a second stroke.
02

Split the Participants

Next, equally divide the 300 participants into two groups of 150. One group will receive aspirin, and the other group will receive Coumadin.
03

Double-blind Procedure

Implement a double-blind procedure where neither the participants nor the administrators know which group is receiving which medicine. This is to avoid bias in the handling of the experiment.
04

Administer the Medication

Give the first group of 150 patients the medication Aspirin, and for the other 150 patients, administer Coumadin. Both group of patients should be checked regularly, and the medicines should be administered for a given period.
05

Collect and Analyze the Data

In the end, collect the data which includes how many patients had a second stroke from both groups. Determine the effectiveness of the medicine by comparing the incidence of second strokes in both groups

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