Folic Acid and Birth Defects. For several years, evidence had been mounting that folic acid reduces major birth defects. A. Creizel and I. Dudas of the National Institute of Hygiene in Budapest directed a study that provided the strongest evidence to date. Their results were published in the paper "Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation" (New England Journal of Medicine, Vol. 327(26). p. 1832 ). For the study, the doctors enrolled women prior to conception and divided them randomly into two groups. One group, consisting of 2701 women, took daily multivitamins containing mg of folic acid; the other group, consisting of 2052 women, received nay A. Creizel and L. Duxlas of the National Institute of Hygiene i) Budapest directed a study that provided the strongest evidence to date Their results were published in the paper "Prevention of the Firs Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation" (New England Journal of Medicine, Vol. 327(26). p. 1832 ). For the study, the doctors enrolled women prior to conception and divided them randomly into two groups. One group, consisting of 2701 women, took daily multivitamins containing mg of folic acid; the other group. consisting of 2052 women, received only trace elements. Major birth defects occurred in 35 cases when the women took folic acid and in 47 cases when the women did not.
a. At the significance level, do the data provide sufficient evidence to conclude that women who take folic acid are at lesser risk of having children with major birth defects?
b. Is this study a designed experiment or an observational study? Explain your answer.
c. In view of your answers to parts (a) and (b), could you reasonably conclude that taking folic acid causes a reduction in major birth defects? Explain your answer.
Explanations 
Textbooks 
Flashcards 
91影视 AI 
Notes 
Study Plans 
Study Sets 
Find a degree 
Magazine 
