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An issue of Science News reported that the Women's Health Initiative cast doubts on the benefit of hormone-replacement therapy. Researchers randomly divided \(4532\) healthy women over the age of \(65\) years into two groups. One group, consisting of \(2229\) women received hormone-replacement therapy; the other group consisting of \(2303\) women, received placebo. Over \(5\) years, \(40\) of the women receiving the hormone-replacement therapy were diagnosed with dementia, compared with \(21\) of those getting placebo.

a. At the \(5%\) significance level, do the data provide sufficient evidence to conclude that healthy women over \(65\) years old who take hormone-replacement therapy are at great risk for dementia than those who do not?

b. Determine and interpret a \(90%\) confidence interval for the difference in dementia risk rates for healthy women over \(65\) years old who take hormone-replacement therapy and those who do not.

Short Answer

Expert verified

Part a. The data provide sufficient evidence to conclude that healthy women over years old who take hormone replacement therapy are at greater risk for dementia than those who do not.

Part b. There is \(90%\) interval for the difference between the proportions is \((0.00317, 0.01448)\).

Step by step solution

01

Part a. Step 1. Given information

The given values are, \(x_{1}=40, n_{1}=2229, x_{2}=21, n_{2}=2303, \alpha=0.05\)

02

Part a. Step 2. Calculation

Using MINITAB output.

MINITAB output: Test and CI two proportions

From the MINITAB, the test statistic is \(2.58\) and the \(p-\)value is \(0.005\).

\(p-\)value is lesser than the level of significance.

\(p-\)value \((=0.005)<a(=0.05)\)

Using the rejection rule, it can be concluded that there is evidence to reject null hypothesis \(H_{0}\): at \(\alpha =0.005\).

Therefore, the data provide sufficient evidence to conclude that healthy women over \(65\) years old who take hormone replacement therapy are at greater risk for dementia than those who do not.

03

Part b. Step 1. Explanation

Using the INITAB output.

MINITAB output: Test and CI for two proportions.

From the MINITAB output, the \(90%\) confidence interval for the difference in dementia risk rate for healthy women over \(65\) years old who take hormone replacement therapy and those who do not is \((0.00317, 0.01448)\).

Therefore, there is \(90%\) interval for the difference between the proportions is \((0.00317, 0.01448)\).

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Most popular questions from this chapter

Women in the Labor Force. The Organization for Economic Cooperation and Development (OFCD) summarizes data on labor-force participation rates in O E C D in Figures. Independent simple random samples were taken of 300 U.S. women and 250 Canadian women. Of the U.S. women, 215 were found to be in the labor force; of the Canadian women. 186 were found to be in the labor force.

a. At the 5%significance level, do the data suggest that there is a difference between the labor-force participation rates of U.S. and Canadian women?

b. Find and interpret a 95% confidence interval for the difference between the labor-force participation rates of U.S. and Canadian women.

Prerequisites to this exercise are Exercises . Why do your graphs in parts (c) of those exercises illustrate the impact of increasing sample size on sampling error? Explain your answer.

In this Exercise, we have given the number of successes and the sample size for a simple random sample from a population. In each case,

a. use the one-proportion plus-four z-interval procedure to find the required confidence interval.

b. compare your result with the corresponding confidence interval found in Exercise 11.25-11.30, if finding such a confidence interval was appropriate.

role="math" localid="1651327118166" x=35,n=50,99%level

The Quinnipiac University Poll conducts nationwide surveys as a public service and for research. In one poll. participants were asked whether they thought eliminating the federal gas tax for the summer months is a good idea. The following problems are based on the results of that poll.

a. Of611Republicans, 275thought it a good idea, and, of 872Democrats, 366thought it a good idea. Obtain a 90%confidence interval for the difference between the proportions of Republicans and Democrats who think that eliminating the federal gas tax for the summer months is a good idea.

b. Of 907women,417thought it a good idea, and, of 838men, 310thought it a good idea. Obtain a90% confidence interval for the difference between the percentages of women and men who think that eliminating the federal gas tax for the summer months is a good idea.

Obtain a sample size that will ensure a margin of error of at most the one specified.

Margin of error=0.02

Confidence level=95%

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