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Suppose a test is given to determine if a person is infected with HIV. If a person is infected with HIV, the test will detect it in \(90 \%\) of the cases; and if the person is not infected with HIV, the test will show a positive result \(3 \%\) of the time. If we assume that \(2 \%\) of the population is actually infected with HIV, what is the probability that a person obtaining a positive result is actually infected with HIV?

Short Answer

Expert verified
The probability that a person who obtained a positive result is actually infected with HIV is approximately 0.3797, or 37.97%.

Step by step solution

01

Define the Problem Variables

We can define the following variables for the problem: \(\n P(D) =\) Probability that a person is actually HIV positive = 0.02, \(\n P(D') =\) Probability that a person is actually HIV negative = 1 - P(D) = 0.98, \(\n P(T|D) =\) Probability that the test is positive given that the person is HIV positive = 0.9, \(\n P(T|D') =\) Probability that the test is positive given that person is HIV negative = 0.03. \(\n We are looking for P(D|T) =\) Probability that a person is actually HIV positive given that the test is positive.
02

Apply Bayes' Theorem

We can use Bayes' Theorem to find the answer, Bayes' Theorem is given by: \[ P(D|T) = \frac{P(T|D) * P(D)}{P(T)} \] We can solve for P(T) using The Law of Total Probability, which states that P(T) = P(T and D) + P(T and D'), and substituting from the expression of and, we get P(T) = P(T|D) * P(D) + P(T|D') * P(D').
03

Substitute the Known Values

Substituting the known values in the equation from step 2, we get P(T) = (0.9*0.02) + (0.03*0.98) = 0.018 + 0.0294 = 0.0474.
04

Calculate P(D|T)

Substituting the known values in the equation of Bayes' Theorem, we get P(D|T) = (0.9*0.02) / 0.0474 = 0.3797.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Conditional Probability
Conditional probability is a fundamental concept in statistics that refers to the likelihood of an event occurring, given that another event has already occurred. In simpler terms, it answers the question: 'How does the probability of an event change when we have extra information about a related event?'

For instance, in the context of our exercise, the condition is having a positive HIV test result (\( T \)). We are interested in the probability of actually being HIV positive (\( D \)) given this positive test result. This is denoted by the notation \( P(D|T) \) and is what conditional probability helps us understand. In practice, conditional probability proves essential for making informed decisions in various fields, such as medical diagnostics and risk assessment.

Practical Example of Conditional Probability

If you were told that someone tested positive for HIV, your natural question would be about the accuracy of the test itself. Here, the test accuracy for an HIV-positive individual is 90%, but the probability of a false positive is 3%, showing the importance of understanding these conditions in assessing the test's reliability.
HIV Infection Probability
When dealing with sensitive health issues such as HIV infection, it is vital to consider the real-world implications of statistical probabilities. The exercise presents us with a population where the actual HIV infection rate is 2%, but the probabilities related to testing add another layer to understanding the risks and implications.

To translate these statistical terms into a more tangible example, imagine a community of 1000 individuals. Given the rate of 2%, we'd expect that around 20 of these individuals are actually HIV positive. However, when testing is executed, factors like false positives and false negatives cannot be ignored and will affect the outcome. Such nuances highlight the importance of interpreting test results with a clear understanding of underlying probabilities to avoid misdiagnosis and the associated emotional and treatment implications.

Applying Probability to Medical Testing

In our case, the probability that a person actually has HIV, given a positive test result (\( P(D|T) \)), is not solely dependent on the test's positive outcome but must be evaluated in the context of the test's reliability and the initial likelihood of infection in the general population.
Law of Total Probability
The Law of Total Probability is an essential principle in probability theory that allows us to break down complex events into simpler, more manageable parts. It effectively combines the probabilities of multiple mutually exclusive events to arrive at the overall probability of a specific event occurring.

This law is particularly useful when we do not have direct information about an event but do have probabilities for a set of related outcomes. For example, to find the overall probability of getting a positive HIV test result (\( P(T) \)), we don't look at just one scenario; instead, we consider both scenarios where the subject is either HIV positive or not, as evaluated in our exercise.

Breaking Down Complex Events

Imagine dividing a sample space into sections representing different outcomes. The Law of Total Probability allows you to calculate the overall probability by adding the individual probabilities of each section. In healthcare, this enables the analysis of a test's overall reliability, incorporating both the rate of correctly identifying a condition and the rate of false positives.

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