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There is a 5050 chance that the queen carries the gene for hemophilia. If she is a carrier, then each prince has a 5050 chance of having hemophilia. If the queen has had three princes without the disease, what is the probability that the queen is a carrier? If there is the fourth prince, what is the probability that he will have hemophilia?

Short Answer

Expert verified

Events Ei, that the i-th son is a hemophiliac are conditionally independent given that the queen is carrier(C)

PCE1cE2cE3c=19PE4E1cE2cE3c=118.

Step by step solution

01

Given Information

Events

C - the Queen is a carrier

Ei - the Queen's i-th son is a hemophiliac

Probabilities:

P(C)=12

PEiC=12

PEiCc=0

Events Eiare independent given C.

02

Explanation

Compute:PCE1cE2cE3c,PE4E1cE2cE3c,

Start with the definition of conditional probability:

PCE1cE2cE3c=PCE1cE2cE3cPE1cE2cE3c

Condition upon whether the queen is a carrier:

PCE1cE2cE3c=PE1cE2cE3cCP(C)PE1cE2cE3cCP(C)+PE1cE2cE3cCcPCc
03

Explanation

Apply the conditional independence of Ei's - probability of intersection is the product of probabilities

PCE1cE2cE3c=PE1cCPE2cCPE3cCP(C)PE1cCPE2cCPE3cCP(C)+PE1cCcPE2cCcPE3cCcPCc

Substitute PEicC=1/2,P(C)=PCc=1/2,PEicCc=1:

PCE1cE2cE3c=124124+1312

=19

04

Explanation

PE4E1cE2cE3c

Calculate the probability by conditioning upon C. This is the Bayes formula with conditional probability PE1cE2cE3c

PE4E1cE2cE3c=PE4CE1cE2cE3c+PE4CcE1cE2cE3c

=PE4CE1cE2cE3cPCE1cE2cE3c+PE4CcE1cE2cE3cPCcE1cE2cE3c

Since events Ei are conditionally independent given C or Cc, the conditioning upon more E1c,E2c,E3c can be removed.

PE4E1cE2cE3c=PE4CPCE1cE2cE3c+PE4CcPCcE1cE2cE3c

=1219+089

=118

05

Final Answer

Events Ei, that the i-th son is a hemophiliac are conditionally independent given that the queen is carrier (C):

PCE1cE2cE3c=19PE4E1cE2cE3c=118

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