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A certain drug is effective in treating a disease if the concentration remains above \(100 \mathrm{mg} / \mathrm{L}\). The initial concentration is \(640 \mathrm{mg} / \mathrm{L}\). It is known from laboratory experiments that the drug decays at the rate of \(20 \%\) of the amount present each hour. a. Formulate a model representing the concentration at each hour. b. Build a table of values and determine when the concentration reaches \(100 \mathrm{mg} / \mathrm{L}\).

Short Answer

Expert verified
The concentration drops below 100 mg/L at about 9 hours.

Step by step solution

01

Understand the Decay Process

The concentration of the drug decreases by 20% of the current amount every hour. This is an example of exponential decay.
02

Write the Exponential Decay Formula

The formula for exponential decay is given by: \( C(t) = C_0 (1 - r)^t \) where \( C(t) \) is the concentration at time \( t \), \( C_0 \) is the initial concentration, and \( r \) is the decay rate.
03

Substitute Known Values into the Formula

We know the initial concentration, \( C_0 = 640 \) mg/L, and the decay rate, \( r = 0.2 \). Therefore, the equation becomes \( C(t) = 640(0.8)^t \).
04

Create a Table of Values

Calculate \( C(t) \) for several values of \( t \) to determine at what hour the concentration drops below 100 mg/L. Start with \( t = 0, 1, 2, \ldots \) until the concentration falls under 100 mg/L.
05

Perform Calculations for Each Hour

Calculate:- \( t = 0, C(0) = 640 \)- \( t = 1, C(1) = 640 \times (0.8)^1 = 512 \)- \( t = 2, C(2) = 640 \times (0.8)^2 = 409.6 \)- \( t = 3, C(3) = 640 \times (0.8)^3 = 327.68 \)- Continue these calculations until the concentration is 100 mg/L or less.
06

Identify When the Concentration is below 100 mg/L

Continue the calculations:- \( t = 4, C(4) = 262.144 \)- \( t = 5, C(5) = 209.7152 \)- \( t = 6, C(6) = 167.77216 \)- \( t = 7, C(7) = 134.217728 \)- \( t = 8, C(8) = 107.3741824 \)- \( t = 9, C(9) = 85.89934592 \)The concentration first goes below 100 mg/L between t = 8 and t = 9 hours.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Drug Concentration Decay Modeling
Imagine a drug that needs to remain effective within your body. For it to work, it must stay above a specific concentration level. In this case, we're looking at a drug with an initial concentration of 640 mg/L that needs to remain effective above 100 mg/L. Understanding how this drug's concentration changes over time in the bloodstream is key. This involves tracking how the concentration dwindles or decays.
One critical factor is that the drug experiences a decay of 20% each hour. This means every hour, the concentration isn't just dropping by a fixed amount - it's decreasing by a percentage of whatever amount is present at that time. This kind of decay is what we refer to as exponential decay.
By creating a model of this decay, we can predict when the drug's concentration will fall below the needed level. This predictive ability is vital, especially in medicine, to ensure that drugs are administered at the right intervals.
Exponential Decay Formula
To mathematically capture how the drug declines over time, we use the exponential decay formula. This formula is a powerful tool, ideal for processes where a quantity diminishes at a rate proportional to its current value. The general model is denoted as:
  • \( C(t) = C_0 (1 - r)^t \)
Here's what each part means:
  • \( C(t) \): The concentration at time \( t \)
  • \( C_0 \): The initial concentration (here, 640 mg/L)
  • \( r \): The decay rate (in our problem, 0.2 or 20%)
  • \( t \): Time in hours
Substituting the known values into the formula, we get \( C(t) = 640(0.8)^t \). This equation tells us how much of the drug remains after \( t \) hours. The decay in this case is due to the reduction that occurs with each passing hour, which we can predict using this model.
Using such a formula, we can calculate the concentration at any given time \( t \), and determine when it becomes ineffective.
Step-by-Step Mathematical Modeling
To model this decay accurately, we follow a step-by-step process to ensure precision in our calculations. Organizing in steps allows us not just to see the progression but also to easily check our work.To start, we rejected the initial concentration and decay rate values into the exponential decay formula, \( C(t) = 640(0.8)^t \). This gives us a clear path to mapping the drug's concentration over time.
Next, creating a table of values helps illustrate the pattern of decay. By calculating \( C(t) \) for each hour, we see how the concentration decreases. We measured values like:
  • \( C(0) = 640 \)
  • \( C(1) = 512 \)
  • \( C(2) = 409.6 \)
  • Continue this until you observe the concentration falling below 100 mg/L.
As calculated, between \( t = 8 \) and \( t = 9 \), the concentration slips below the effective threshold, dropping to approximately 85.9 mg/L by \( t = 9 \). Ensuring calculations are listed step-by-step consolidates our understanding and verifies the answer. This methodical approach boosts clarity and helps in replicating results as needed, like adjusting parameters for alternate examples or exact dosing needs.

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