Chapter 4: Q2P (page 91)
Use Table 4-1 to state what fraction of a Gaussian population lies within the following intervals:
(a)
(b)
(c)to
(d)to
(e)to
Short Answer
a) 0.6826
b) 0.9546
c) 0.3413
d) 0.1915
e) 0.1498
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Chapter 4: Q2P (page 91)
Use Table 4-1 to state what fraction of a Gaussian population lies within the following intervals:
(a)
(b)
(c)to
(d)to
(e)to
a) 0.6826
b) 0.9546
c) 0.3413
d) 0.1915
e) 0.1498
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The percentage of an additive in gasoline was measured six times with the following results:. Find the andconfidence intervals for the percentage of the additive
Sample 8 of Problem 4-3 was analyzed seven times, with and s=0.00007. Find the 99 % confidence interval for sample 8 .
Suppose that you carry out an analytical procedure to generate a linear calibration curve like that shown in Figure 4-13. Then you analyse an unknown and find an absorbance that gives a negative concentration for the analyte. What might this mean?
Blood plasma proteins of patients with malignant breast tumors differ from proteins of healthy people in their solubility in the presence of various polymers. When the polymers dextran and poly(ethylene glycol) are mixed with water, a two-phase mixture is formed. When plasma proteins of tumor patients are added, the distribution of proteins between the two phases is different from that of plasma proteins of a healthy person. The distribution coefficient ( K) for any substance is defined as K =[concentration of the substance in phase[concentration of the substance in phase B ]. Proteins of healthy people have a mean distribution coefficient of 0.75 with a standard deviation of 0.07. For the proteins of people with cancer, the mean is 0.92 with a standard deviation of 0.11.
(a) Suppose that Kwere used as a diagnostic tool and that a positive indication of cancer is taken as. What fraction of people with tumors would have a false negative indication of cancer because?
(b) What fraction of healthy people would have a false positive indication of cancer? This number is the fraction of healthy people with, shown by the shaded area in the graph below. Estimate an answer with Table 4 - 1 and obtain a more exact result with the NORMDIST function in Excel.
(c) Vary the first argument of the NORMDIST function to select a distribution coefficient that would identify 75% of people with tumors. That is, 75% of patients with tumors would have K above the selected distribution coefficient. With this value of K, what fraction of healthy people would have a false positive result indicating they have a tumor?

What fraction of vertical bars in Figure 4-5a is expected to include the population mean (10000) if many experiments are carried out? Why are the 90 % confidence interval bars longer than the 50 % bars in Figure 4-5?
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