Chapter 24: Problem 78
When samples of double-stranded DNA are analyzed, the quantity of adenine present equals that of thymine. Similarly, the quantity of guanine equals that of cytosine. Explain the significance of these observations.
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Chapter 24: Problem 78
When samples of double-stranded DNA are analyzed, the quantity of adenine present equals that of thymine. Similarly, the quantity of guanine equals that of cytosine. Explain the significance of these observations.
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(a) True or false: Alkenes undergo addition reactions and aromatic hydrocarbons undergo substitution reactions. (b) Using condensed structural formulas, write the balanced equation for the reaction of 2 -pentene with \(\mathrm{Br}_{2}\) and name the resulting compound. Is this an addition or a substitution reaction? (c) Write a balanced chemical equation for the reaction of \(\mathrm{Cl}_{2}\) with benzene to make para-dichlorobenzene in the presence of \(\mathrm{FeCl}_{3}\) as a catalyst. Is this an addition or a substitution reaction?
The protein ribonuclease \(A\) in its native, or most stable, form is folded into a compact globular shape: Native ribonuclease A (a) Does the native form have a lower or higher free energy than the denatured form, in which the protein is an extended chain? (b) What is the sign of the system's entropy change in going from the denatured to the folded form? (c) In the native form, the molecule has four \(-5-5\) - bonds that bridge parts of the chain. What effect do you predict these four linkages to have on the free energy and entropy of the native form relative to the free energy and entropy of a hypothetical folded structure that does not have any - \(\mathrm{S}-\mathrm{S}\) linkages? Explain. (d) A gentle reducing agent converts the four - \(S-S\) - linkages in ribonuclease A to eight - \(\mathrm{S}-\mathrm{H}\) bonds. What effect do you predict this conversion to have on the tertiary structure and entropy of the protein? (e) Which amino acid must be present for - SH bonds to exist in ribonuclease A?
Give the name or condensed structural formula, as appropriate:
(a)
Write the condensed structural formula for each of the following compounds: (a) 2-pentanol, (b) 1,2-propanediol, (c) ethyl acetate, (d) diphenyl ketone, (e) methyl ethyl ether.
Predict the ideal values for the bond angles about each carbon atom in the following molecule. Indicate the hybridization of orbitals for each carbon. $$ \mathrm{CH}_{3} \mathrm{CCCH}_{2} \mathrm{COOH} $$
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