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(a) Draw the condensed structure of the tripeptide Gly-GlyHis. (b) How many different tripeptides can be made from the amino acids glycine and histidine? Give the abbreviations for each of these tripeptides, using the three-letter and one-letter codes for the amino acids.

Short Answer

Expert verified
The condensed structure of the tripeptide Gly-Gly-His is H2N-CH2-CO-NH-CH2-CO-NH-CH(C3H2N2)-COOH. There are 8 different tripeptides that can be made from glycine (Gly) and histidine (His): Gly-Gly-Gly (GGG), Gly-Gly-His (GGH), Gly-His-Gly (GHG), Gly-His-His (GHH), His-Gly-Gly (HGG), His-Gly-His (HGH), His-His-Gly (HHG), and His-His-His (HHH).

Step by step solution

01

Drawing the condensed structure of Gly-Gly-His tripeptide

To draw the condensed structure of the tripeptide Gly-Gly-His, we need to know the structure of the amino acids glycine (Gly) and histidine (His). Glycine (Gly) structure: H2N-CH2-COOH Histidine (His) structure: H2N-CH(C3H2N2)-COOH Now, we will join two Gly molecules and then add one His molecule to form the tripeptide (Gly-Gly-His). Glycine (Gly) + Glycine (Gly) -> H2N-CH2-CO-NH-CH2-COOH Gly-Gly + Histidine (His) -> H2N-CH2-CO-NH-CH2-CO-NH-CH(C3H2N2)-COOH So, the condensed structure of the tripeptide Gly-Gly-His is: H2N-CH2-CO-NH-CH2-CO-NH-CH(C3H2N2)-COOH
02

Calculate the number of tripeptides made from glycine and histidine

To find out the number of different tripeptides that can be made using glycine (Gly) and histidine (His) amino acids, we can use the permutation formula. In this case, we have 2 different amino acids to choose from, and we need to choose 3 to make a tripeptide. So, the number of permutations is given by: \(No.\:of\:tripeptides = N^n = 2^3\) where N = 2 (number of amino acids to choose from) and n = 3 (number of amino acids in a tripeptide).
03

Write the abbreviations for each of the tripeptides

Calculating the number of tripeptides from the permutation formula gives us: No. of tripeptides = 2^3 = 8 These 8 tripeptides and their abbreviations are: 1. Gly-Gly-Gly (GGG) 2. Gly-Gly-His (GGH) 3. Gly-His-Gly (GHG) 4. Gly-His-His (GHH) 5. His-Gly-Gly (HGG) 6. His-Gly-His (HGH) 7. His-His-Gly (HHG) 8. His-His-His (HHH)

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