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(a) Explain the importance of enzymes in biological systems. (b) What chemical transformations are catalyzed (i) by the enzyme catalase, (ii) by nitrogenase?

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(a) Enzymes are essential in biological systems as they act as catalysts, increasing the rate of chemical reactions and maintaining cellular processes. They lower the activation energy required for a reaction, enabling them to occur at sufficient speeds to sustain life. Enzymes also contribute to the regulation of cellular processes by responding to environmental changes. (b) (i) Catalase catalyzes the breakdown of hydrogen peroxide (Hâ‚‚Oâ‚‚) into water and oxygen gas, reducing potential damage from reactive oxygen species: \(2H_{2}O_{2} \rightarrow 2H_{2}O + O_{2}\) (ii) Nitrogenase facilitates biological nitrogen fixation by converting atmospheric nitrogen into ammonia, crucial for the synthesis of biomolecules in plants and other organisms: \(N_{2} + 8H^{+} + 8e^{-} + 16ATP \rightarrow 2NH_{3} + H_{2} + 16ADP + 16P_{i}\)

Step by step solution

01

(a) Importance of enzymes in biological systems

Enzymes are specialized proteins that act as catalysts in biological systems, which means they help increase the rate of chemical reactions. Enzymes are crucial in maintaining the proper functioning of living organisms, as they ensure that cellular processes occur at sufficient speeds to sustain life. They do this by lowering the activation energy required for a chemical reaction to occur, thus making it easier for the reaction to take place. Examples of processes that involve enzymes include digestion, metabolism, and DNA replication. In addition to their role in speeding up reactions, enzymes also contribute to regulation of cellular processes by responding to changes in the cell's environment, such as pH or temperature.
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(b) (i) Chemical transformations catalyzed by the enzyme catalase

Catalase is an enzyme that is found in almost all living organisms and has a crucial role in breaking down the toxic compound hydrogen peroxide (Hâ‚‚Oâ‚‚), which is a byproduct of cellular respiration. The chemical transformation catalyzed by catalase can be represented by the following reaction: \(2H_{2}O_{2} \rightarrow 2H_{2}O + O_{2}\) In this reaction, catalase converts two molecules of hydrogen peroxide into two molecules of water and one molecule of oxygen gas. This breakdown reduces the potential damage of reactive oxygen species (ROS) that can damage cellular components, such as proteins, lipids, and nucleic acids.
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(b) (ii) Chemical transformations catalyzed by nitrogenase

Nitrogenase is an enzyme complex that plays a vital role in the process of biological nitrogen fixation. This process refers to the conversion of atmospheric nitrogen (N₂) into ammonia (NH₃), which can then be utilized by plants and other organisms as a building block for amino acids, nucleic acids, and other essential biomolecules. The chemical transformation catalyzed by nitrogenase can be represented by the following reaction: \(N_{2} + 8H^{+} + 8e^{-} + 16ATP \rightarrow 2NH_{3} + H_{2} + 16ADP + 16P_{i}\) In this reaction, nitrogenase facilitates the reduction of nitrogen gas into two molecules of ammonia, with the concomitant production of one molecule of hydrogen gas. The reaction also involves the transfer of electrons and the hydrolysis of ATP, providing the energy needed for the process. Nitrogenases are mainly found in some bacteria, such as those living in symbiotic relationships with legume plants, which can provide the nitrogen compounds needed for plant growth.

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Most popular questions from this chapter

The isomerization of methyl isonitrile \(\left(\mathrm{CH}_{3} \mathrm{NC}\right)\) to acetonitrile \(\left(\mathrm{CH}_{3} \mathrm{CN}\right)\) was studied in the gas phase at \(215^{\circ} \mathrm{C}\), and the following data were obtained: $$ \begin{array}{ll} \hline \text { Time (s) } & \text { [CH }_{3} \text { NC] (M) } \\ \hline 0 & 0.0165 \\ 2,000 & 0.0110 \\ 5,000 & 0.00591 \\ 8,000 & 0.00314 \\ 12,000 & 0.00137 \\ 15,000 & 0.00074 \\ \hline \end{array} $$ (a) Calculate theaverage rate of reaction, in \(M / \mathrm{s}\), for the time interval between each measurement. (b) Graph \(\left[\mathrm{CH}_{3} \mathrm{NC}\right]\) versus time, and determine the instantaneous rates in \(\mathrm{M} / \mathrm{s}\) at \(t=5000 \mathrm{~s}\) and \(t=8000 \mathrm{~s}\).

There are literally thousands of enzymes at work in complex living systems such as human beings. What properties of the enzymes give rise to their ability to distinguish one substrate from another?

NO catalyzes the decomposition of \(\mathrm{N}_{2} \mathrm{O}\), possibly by the following mechanism: $$ \begin{array}{r} \mathrm{NO}(\mathrm{g})+\mathrm{N}_{2} \mathrm{O}(\mathrm{g}) \longrightarrow \mathrm{N}_{2}(g)+\mathrm{NO}_{2}(g) \\ 2 \mathrm{NO}_{2}(g) \longrightarrow 2 \mathrm{NO}(g)+\mathrm{O}_{2}(g) \end{array} $$ (a) What is the chemical equation for the overall reaction? Show how the two steps can be added to give the overall equation. (b) Why is NO considered a catalyst and not an intermediate? (c) If experiments show that during the decomposition of \(\mathrm{N}_{2} \mathrm{O}, \mathrm{NO}_{2}\) does not accumulate in measurable quantities, does this rule out the proposed mechanism? If you think not, suggest what might be going on.

The rate of the reaction \(\mathrm{CH}_{3} \mathrm{COOC}_{2} \mathrm{H}_{5}(a q)+\mathrm{OH}^{-}(a q) \longrightarrow\) \(\mathrm{CH}_{3} \mathrm{COO}^{-}(a q)+\mathrm{C}_{2} \mathrm{H}_{5} \mathrm{OH}(a q)\) was measured at several temperatures, and the following data were collected: $$ \begin{array}{ll} \hline \text { Temperature }\left({ }^{\circ} \mathrm{C}\right) & k\left(\mathrm{M}^{-1} \mathrm{~s}^{-1}\right) \\ \hline 15 & 0.0521 \\ 25 & 0.101 \\ 35 & 0.184 \\ 45 & 0.332 \end{array} $$ Using these data, graph \(\ln k\) versus \(1 / T\). Using your graph, determine the value of \(E_{g}\)

Consider two reactions. Reaction (1) has a constant halflife, whereas reaction (2) has a half-life that gets longer as the reaction proceeds. What can you conclude about the rate laws of these reactions from these observations?

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