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Problem 3

Which of the following statements about DNA polymerases is NOT accurate? a. They are enzymes. b. They make DNA polymers by adding nucleotides to the \(3^{\prime}\) end of a growing chain. c. They require ATP for addition of each nucleotide to a growing strand. d. They require a single-stranded template.

Problem 3

. Which of the following is an accurate distinction between DNA polymerases in \(E\). coli? a. DNA Pol I synthesizes the leading strand, and DNA Pol III synthesizes the lagging strand. b. DNA Pol III synthesizes the leading strand, and DNA Pol I synthesizes Okazaki fragments. c. DNA Pol III requires a free \(3^{\prime}\) OH to add a nucleotide to a growing strand; DNA Pol I does not. d. DNA Pol I and DNA Pol III play a role in DNA replication; DNA Pol II is involved in DNA repair.

Problem 3

Chargaff studied the composition of DNA from different sources and found that a. the number of phosphate groups always equals the number of 5 -carbon sugars. b. the proportion of A equals that of \(\mathrm{C}\) and the proportion of \(\mathrm{G}\) equals that of \(\mathrm{T}\) c. the proportion of A equals that of \(\mathrm{T}\) and the proportion of \(\mathrm{G}\) equals that of \(\mathrm{C}\). d. purines bind to pyrimidines.

Problem 4

Which of the following is NOT part of the Watson-Crick model of the structure of DNA? a. DNA is composed of two strands. b. The two DNA strands are oriented in parallel \(\left(5^{\prime}-\right.\) to- \(\left.3^{\prime}\right)\). c. Purines bind to pyrimidines. d. DNA forms a double helix.

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