/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Problem 17 Scientists currently believe tha... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 17: Problem 17

Scientists currently believe that the main barrier to the filtration of proteins into the glomerular capsule is the a. capillary fenestrae. b. basement membrane. c. slit diaphragm. d. macula densa.

Short Answer

Expert verified
The main barrier to the filtration of proteins into the glomerular capsule is the slit diaphragm (Option C). It prevents the passage of larger molecules like proteins, allowing only smaller molecules to pass through.

Step by step solution

01

Understanding Glomerular Filtration Barriers

The filtration process in the glomerulus takes place across three barriers: the capillary fenestrae, the basement membrane, and the slit diaphragm. These barriers ensure selective filtration of molecules from the blood into the glomerular capsule.
02

Option A: Capillary Fenestrae

Capillary fenestrae are small pores in the endothelial cells of glomerular capillaries. These pores allow the passage of water, ions, glucose, amino acids, and other small molecules but not larger molecules like proteins and blood cells.
03

Option B: Basement Membrane

The basement membrane sits between the capillary fenestrae and the podocytes, which form the slit diaphragm. It is composed of extracellular matrix and acts as a size-selective barrier, allowing smaller molecules to pass through, while larger molecules, like proteins, are generally excluded.
04

Option C: Slit Diaphragm

The slit diaphragm is formed by the interdigitating podocyte foot processes, which wrap around the capillary loops. The slit diaphragm serves as a final barrier for filtration and prevents the passage of larger molecules like proteins.
05

Option D: Macula Densa

Macula densa is a group of specialized cells in the distal convoluted tubule that comes into contact with the afferent arteriole, regulating glomerular filtration rate and blood pressure. However, it is not involved in the filtration process itself.
06

The Main Barrier

Among the provided options, the main barrier to the filtration of proteins into the glomerular capsule would be the slit diaphragm (Option C). It prevents the passage of larger molecules like proteins, allowing only smaller molecules to pass through.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Describe how the thiazide diuretics, loop diuretics, and osmotic diuretics work.

The kidneys help to maintain acid-base balance by a. the secretion of \(\mathrm{H}^{+}\)in the distal regions of the nephron. b. the action of carbonic anhydrase within the apical plasma membranes. c. the action of carbonic anhydrase within the cytoplasm of the tubule cells. d. the buffering action of phosphates and ammonia in the urine. e. all of these means.

What are xenobiotics, and how are we able to quickly eliminate them in the urine? Describe the carriers involved, and how they can transport many different molecules. Explain how this elimination of xenobiotics can sometimes interfere with medical treatment.

Which of these factors oppose(s) filtration from the glomerulus? a. plasma oncotic pressure b. hydrostatic pressure in glomerular (Bowman's) capsule c. plasma hydrostatic pressure d. both \(a\) and \(b\) e. both \(b\) and \(c\)

2\. Active transport of sodium; water follows passively a. Proximal tubule b. Descending limb of loop c. Ascending limb of loop d. Distal tubule e. Medullary collecting duct
See all solutions

Recommended explanations on Biology Textbooks

Cells

Read Explanation

Biological Molecules

Read Explanation

Substance Exchange

Read Explanation

Control of Gene Expression

Read Explanation

Microbiology

Read Explanation

Cellular Energetics

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.