/*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} Problem 5 One way that bacterial cells reg... [FREE SOLUTION] | 91影视

91影视

Log out

Learning Materials

Features

Discover

Chapter 11: Problem 5

One way that bacterial cells regulate DNA replication is through GATC methylation sites within the origin of replication. Would this mechanism work if the DNA was conservatively (rather than semiconservatively) replicated?

Short Answer

Expert verified
No, the mechanism of GATC methylation wouldn't work effectively if DNA was conservatively replicated, as it would lack a reliable process to discriminate the 'old' from the 'new' DNA based on methylation status.

Step by step solution

01

Understand DNA Replication Types

Firstly, understand the difference between semiconservative and conservative replication of DNA. In semiconservative replication, each original strand of DNA molecule serves as a template, resulting in two new DNA strands, each composed of one old and one new strand. On the contrary, conservative replication suggests that the entire original DNA molecule serves as a template for a totally new molecule.
02

Understand GATC Methylation Sites Role

Next, understand what role GATC methylation sites play in DNA replication in bacterial cells. In bacterial DNA, adenine residues in GATC sequences get methylated shortly after replication. This methylation, delayed on the newly synthesized strand, acts as a marker distinguishing it from the original template strand. It plays a crucial role in verifying correct replication and DNA repair.
03

Evaluate the Mechanism Functioning

Finally, evaluate if this mechanism would function if the DNA was conservatively replicated. Since conservative replication proposes that the entire original DNA serves as a template, if this were the case, there wouldn't be an immediate scheme to distinguish the 'new' from 'old' DNA based on methylation. As such, it seems unlikely that GATC methylation could provide the same regulatory role in a conservative replication model.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Over 30 million students worldwide already upgrade their learning with 91影视!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

A DNA strand has the following sequence: 5'-GATCCCGATCCGCATACATTTACCAGATCACCACC \(-3^{\prime}\) In which direction would DNA polymerase slide along this strand (from left to right or from right to left)? If this strand was used as a template by DNA polymerase, what would be the sequence of the newly made strand? Indicate the \(5^{\prime}\) and \(3^{\prime}\) ends of the newly made strand.

The compound known as nitrous acid is a reactive chemical that replaces amino groups \(\left(-\mathrm{NH}_{2}\right)\) with keto groups \((=\mathrm{O})\). When nitrous acid reacts with the bases in DNA, it can change cytosine to uracil and change adenine to hypoxanthine. A DNA double helix has the following sequence: TTGGATGCTGG AACCTACGACC A. What would be the sequence of this double helix immediately after reaction with nitrous acid? Let the letter \(\mathrm{H}\) represent hypoxanthine and \(U\) represent uracil. B. Let's suppose this DNA was treated with nitrous acid. The nitrous acid was then removed, and the DNA was replicated for two generations. What would be the sequences of the DNA products after the DNA had replicated twice? Your answer should contain the sequences of four double helices. Note: During DNA replication, uracil hydrogen bonds with adenine, and hypoxanthine hydrogen bonds with cytosine.

As discussed in Chapter 18, some viruses contain RNA as their genetic material. Certain RNA viruses can exist as a provirus in which the viral genetic material has been inserted into the chromosomal DNA of the host cell. For this to happen, the viral RNA must be copied into a strand of DNA. An enzyme called reverse transcriptase, encoded by the viral genome, copies the viral RNA into a complementary strand of DNA. The strand of DNA is then used as a template to make a double-stranded DNA molecule. This doublestranded DNA molecule is then inserted into the chromosomal DNA, where it may exist as a provirus for a long period of time. A. How is the function of reverse transcriptase similar to the function of telomerase? B. Unlike DNA polymerase, reverse transcriptase does not have a proofreading function. How might this affect the proliferation of the virus?

List and briefly describe the three types of functionally important sequences within bacterial origins of replication.

Explain the proofreading function of DNA polymerase.
See all solutions

Recommended explanations on Biology Textbooks

Biological Molecules

Read Explanation

Biological Structures

Read Explanation

Heredity

Read Explanation

Cells

Read Explanation

Biological Organisms

Read Explanation

Communicable Diseases

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.