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Chapter 7: Problem 7
What is the relationship between recombination frequency and a centiMorgan?
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Why do calculated recombination frequencies between pairs of loci that are located far apart underestimate the true genetic distances between loci?
In Drosophila melanogaster, ebony body (e) and rough eyes (ro) are encoded by autosomal recessive genes found on chromosome \(3 ;\) they are separated by 20 m.u. The gene that encodes forked bristles \((f)\) is \(X-\) linked recessive and assorts independently of \(e\) and ro. Give the phenotypes of progeny and their expected proportions when a female of each of the following genotypes is test- crossed with a male. $$\text { a. } \frac{e^{+}}{e} \frac{r o^{+}}{r o} \quad \frac{f^{+}}{f}$$ $$\text { b. } \frac{e^{+}}{e} \frac{r o}{r o^{+}} \quad \frac{f^{+}}{f}$$
The introduction to this chapter described the search for genes that determine pattern baldness in humans. In \(1916,\) Dorothy Osborn suggested that pattern baldness is a sex-influenced trait (see Chapter 5 ) that is dominant in males and recessive in females. More research suggested that pattern baldness is an X-linked recessive trait. Would you expect to see independent assortment between genetic markers on the X chromosome and pattern baldness if (a) pattern baldness is sex-influenced and (b) if pattern baldness is X-linked recessive? Explain your answer.
A series of two-point crosses were carried out among seven loci \((a, b, c,\) \(d, e, f, \text { and } g),\) producing the following recombination frequencies. Map the seven loci, showing their linkage groups, the order of the loci in each linkage group, and the distances between the loci of each group.
In German cockroaches, bulging eyes \((b u)\) are recessive to normal eyes \(\left(b u^{+}\right)\) and curved wings \((c v)\) are recessive to straight wings \(\left(c v^{+}\right) .\) These two traits are encoded by autosomal genes that are linked. A cockroach has genotype \(b u^{+} b u c v^{+} c v,\) and the genes are in repulsion. Which of the following sets of genes will be found in the most common gametes produced by this cockroach? a. \(b u^{+} c v^{+}\) b. bu cv c. \(b u^{+} b u\) d. \(c v^{+} c v\) e. \(b u c v^{+}\) Explain your answer.
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