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Full color \((D)\) in domestic cats is dominant over dilute color \((d) .\) Of 325 cats obser ved, 194 have full color and 131 have dilute color. a. If these cats are in Hardy-Weinberg equilibrium for the dilution locus, what is the frequency of the dilute allele? b. How many of the 194 cats with full color are likely to be heterozygous?

Short Answer

Expert verified
The frequency of the dilute allele is approximately 0.633, and about 91 full-color cats are heterozygous.

Step by step solution

01

Understand Hardy-Weinberg Equilibrium

The Hardy-Weinberg equilibrium principle describes a theoretical situation where allele and genotype frequencies in a population remain constant, provided the population is large, mating is random, and there is no selection or mutation. For our exercise, we can use this principle to relate alleles (\(D\) and \(d\)) to genotype frequencies.
02

Define Known Values

From the problem, cats with full color are either homozygous dominant \((DD)\) or heterozygous \((Dd)\), while cats with dilute color are homozygous recessive \((dd)\). We have 131 dilute cats, so \(q^2 = \frac{131}{325}\).
03

Calculate Frequency of Dilute Allele

To find the allele frequency of dilution (\(d\)), calculate \(q\) as follows: \[q = \sqrt{\frac{131}{325}}\] Compute \(q\) using a calculator.
04

Calculate Full Color Allele Frequency

Since the sum of allele frequencies for a gene locus is 1 (\(p + q = 1\)), find \(p\) (frequency of \(D\)) using: \[ p = 1 - q \]
05

Determine Frequency of Heterozygous Genotype

Use the formula for the heterozygous genotype \((2pq)\) to find the proportion of full color cats that are \(Dd\): \[2pq = 2 \times (1-q) \times q\].
06

Calculate Number of Heterozygous Cats

Multiply the proportion of \(Dd\) cats by the total number of full color cats (194): \[ \text{Number of } Dd = 194 \times 2pq \].

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Allele Frequency
The concept of allele frequency is central to understanding population genetics and, specifically, the Hardy-Weinberg equilibrium. It describes how common an allele is within a population. In our scenario involving cats, we are interested in the frequency of the "dilute" allele denoted as \(d\). When we refer to allele frequency, we are essentially measuring the proportion of a specific allele in the gene pool, compared to other alleles for the same trait.

For instance, if we observe 131 out of 325 cats with a dilute color, we are referring to those homozygous recessive \(dd\) cats. To determine the frequency \(q\) of the \(d\) allele, we use their prevalence. The Hardy-Weinberg principle allows us to recognize that \(q^2\) represents the frequency of the homozygous recessive genotype. From here, we find \(q\) by taking the square root of the ratio \(\frac{131}{325}\). This calculation gives us a quantitative measure of how common the dilute allele is in this particular cat population.
Dominant and Recessive Traits
Understanding dominant and recessive traits is crucial in classical genetics and helps evaluate the genetic makeup of organisms within a population. A dominant trait, like full color in cats (denoted as \(D\)), is expressed when at least one dominant allele is present. In contrast, a recessive trait, such as dilute color \(d\), requires two copies of the recessive allele to be displayed phenotypically.

Dominance explains why cats with a dominant allele (\(DD\) or \(Dd\)) will exhibit the full color. Meanwhile, only cats with two recessive alleles (\(dd\)) will have a dilute color. This distinction is key to deciphering genetic problems, as it informs us how to classify genotypes based on observable traits. In terms of breeding and predicting offspring traits, understanding which traits are dominant or recessive allows predictions on the likelihood of certain traits appearing in future generations.
Heterozygous Genotype
A heterozygous genotype occurs when an organism carries two different alleles for a particular gene. Considering our example with cats, a heterozygous genotype would be \(Dd\), meaning one allele for full color is paired with an allele for dilute color. The presence of a dominant trait (D) in the genotype ensures that the organism displays the dominant phenotype, here being full color, despite carrying a gene for a potential recessive trait.

To determine how many of these full-color cats are heterozygous, we calculate \(2pq\). The formula \(2pq\) represents the probability of being heterozygous, where \(p\) is the frequency of allele \(D\), and \(q\) is the frequency of allele \(d\). By multiplying \(2pq\) by the total number of full-color cats, we estimate the number of cats that are carriers for the recessive trait. This process helps geneticists predict gene variations and the feasibility of certain traits being passed to subsequent generations, thereby bridging individual organism genetics with larger population dynamics.

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Most popular questions from this chapter

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