Chapter 25: Problem 25
What genetic changes take place during speciation?
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Chapter 25: Problem 25
What genetic changes take place during speciation?
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In a population of 10,000 individuals, where 3600 are \(M M\) 1600 are \(N N,\) and 4800 are \(M N,\) what are the frequencies of the \(M\) alleles and the \(N\) alleles?
Recent reconstructions of evolutionary history are often dependent on assigning divergence in terms of changes in amino acid or nucleotide sequences. For example, a comparison of cytochrome c shows 10 amino acid differences between humans and dogs, 24 differences between humans and moths, and 38 differences between humans and yeast. Such data provide no information as to the absolute times of divergence for humans, dogs, moths, and yeast. How might one calibrate the molecular clock to an absolute time clock? What problems might one encounter in such a calibration?
Price et al. (1999. J. Bacteriol. 181: 2358-2362) conducted a genetic study of the toxin transport protein (PA) of Bacillus anthracis, the bacterium that causes anthrax in humans. Within the 2294 -nucleotide gene in 26 strains they identified five point mutations-two missense and three synonyms-among different isolates. Necropsy samples from an anthrax outbreak in 1979 revealed a novel missense mutation and five unique nucleotide changes among ten victims. The authors concluded that these data indicate little or no horizontal transfer between different \(B\). anthracis strains. (a) Which types of nucleotide changes (missense or synonyms) cause amino acid changes? (b) What is meant by horizontal transfer? (c) On what basis did the authors conclude that evidence of horizontal transfer is absent from their data?
The genetic difference between two Drosophila species, \(D\). heteroneura and \(D .\) sylvestris, as measured by nucleotide diversity, is about 1.8 percent. The difference between chimpanzees \((P\) troglodytes and humans (H. sapiens) is about the same, yet the latter species are classified in different genera. In your opinion, is this valid? Explain why.
Read the Chapter Concepts list on page \(681 .\) All these pertain to the principles of population genetics and the evolution of species. Write a short essay describing the roles of mutation, migration, and selection in bringing about speciation.
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