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The regions in the eukaryotic genome having duplicated DNA sequences representing evolutionary vestiges of duplicated copies of genes are called Pseudogenes.

1. Non-functional: Pseudogenes are non-functional, meaning they no longer encode protein products. This is due to the accumulation of deleterious mutations over time, such as nucleotide insertions, deletions, or substitutions. 2. Homologous to functional genes: Pseudogenes share sequence homology (similarity) with functional genes, as they are derived from the duplication or retrotransposition of the original gene. 3. Mutations: Pseudogenes are characterized by the accumulation of multiple mutations which render them non-functional. These include point mutations, frame-shift mutations, premature stop codons, and deletion or insertion of large segments of the pseudogene. 4. Transcription: Some pseudogenes are still transcribed into RNA, though they do not produce functional proteins. The resulting RNA may have regulatory functions within the cell. 5. Evolutionary evidence: Pseudogenes provide evolutionary evidence for the duplication and subsequent divergence of genes within the genome. The presence of pseudogenes can help researchers study the evolutionary history of genes and genomes.